Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development

INTRODUCTION: Experimental and clinical evidence points to a critical role of progesterone and the nuclear progesterone receptor (PR) in controlling mammary gland tumorigenesis. However, the molecular mechanisms of progesterone action in breast cancer still remain elusive. On the other hand, micro R...

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Detalles Bibliográficos
Autores principales: Rivas, Martin A, Venturutti, Leandro, Huang, Yi-Wen, Schillaci, Roxana, Huang, Tim Hui-Ming, Elizalde, Patricia V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446340/
https://www.ncbi.nlm.nih.gov/pubmed/22583478
http://dx.doi.org/10.1186/bcr3187

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