Determining sensitivity and specificity of HER2 testing in breast cancer using a tissue micro-array approach

INTRODUCTION: Overexpression of the human epidermal growth factor receptor 2 (HER2) as a result of HER2 gene amplification is associated with a relatively poor prognosis in breast cancer and is predictive of HER2-targeting therapy response. False-positive rates of up to 20% for HER2 testing have bee...

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Detalles Bibliográficos
Autores principales: Dekker, Tim JA, Borg, Susan Ter, Hooijer, Gerrit KJ, Meijer, Sybren L, Wesseling, Jelle, Boers, James E, Schuuring, Ed, Bart, Jos, van Gorp, Joost, Mesker, Wilma E, Kroep, Judith R, Smit, Vincent THBM, van de Vijver, Marc J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446356/
https://www.ncbi.nlm.nih.gov/pubmed/22694844
http://dx.doi.org/10.1186/bcr3208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446356/
https://www.ncbi.nlm.nih.gov/pubmed/22694844
http://dx.doi.org/10.1186/bcr3208

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