Cargando…

Determining sensitivity and specificity of HER2 testing in breast cancer using a tissue micro-array approach

INTRODUCTION: Overexpression of the human epidermal growth factor receptor 2 (HER2) as a result of HER2 gene amplification is associated with a relatively poor prognosis in breast cancer and is predictive of HER2-targeting therapy response. False-positive rates of up to 20% for HER2 testing have bee...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dekker, Tim JA, Borg, Susan Ter, Hooijer, Gerrit KJ, Meijer, Sybren L, Wesseling, Jelle, Boers, James E, Schuuring, Ed, Bart, Jos, van Gorp, Joost, Mesker, Wilma E, Kroep, Judith R, Smit, Vincent THBM, van de Vijver, Marc J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446356/ https://www.ncbi.nlm.nih.gov/pubmed/22694844 http://dx.doi.org/10.1186/bcr3208

Ejemplares similares

Quality assessment of estrogen receptor and progesterone receptor testing in breast cancer using a tissue microarray-based approach
por: Dekker, T. J. A., et al.
Publicado: (2015)

Erratum to: Quality assessment of estrogen receptor and progesterone receptor testing in breast cancer using a tissue microarray-based approach
por: Dekker, T. J. A., et al.
Publicado: (2015)

Retrospective analysis of metastatic behaviour of breast cancer subtypes
por: Savci-Heijink, C. Dilara, et al.
Publicado: (2015)

The dynamics of HER2 status in esophageal adenocarcinoma
por: Creemers, Aafke, et al.
Publicado: (2018)

Response to HER2 Inhibition in a Patient With Brain Metastasis With EGFR TKI Acquired Resistance and an HER2 Amplification
por: Meedendorp, Arenda D., et al.
Publicado: (2018)

Chemotherapy resistance and stromal targets in breast cancer treatment: a review
por: van der Spek, Y. M., et al.
Publicado: (2020)

Fully Automated Fluorescent in situ Hybridization (FISH) Staining and Digital Analysis of HER2 in Breast Cancer: A Validation Study
por: van der Logt, Elise M. J., et al.
Publicado: (2015)

Tumor‐stroma ratio is associated with Miller‐Payne score and pathological response to neoadjuvant chemotherapy in HER2‐negative early breast cancer
por: Hagenaars, Sophie C., et al.
Publicado: (2021)

The role of artificial intelligence to quantify the tumour-stroma ratio for survival in colorectal cancer
por: Smit, Marloes A, et al.
Publicado: (2020)

Discordance in HER2 Status in Gastro-esophageal Adenocarcinomas: A Systematic Review and Meta-analysis
por: Creemers, A., et al.
Publicado: (2017)

Tumor‐immune landscape patterns before and after chemoradiation in resectable esophageal adenocarcinomas
por: Soeratram, Tanya TD, et al.
Publicado: (2021)

Allele-specific regulation of FGFR2 expression is cell type-dependent and may increase breast cancer risk through a paracrine stimulus involving FGF10
por: Huijts, Petra EA, et al.
Publicado: (2011)

Epithelial-to-mesenchymal transition status of primary breast carcinomas and its correlation with metastatic behavior
por: Savci-Heijink, C. D., et al.
Publicado: (2019)

The clinical value of HER-2 overexpression and PIK3CA mutations in the older breast cancer population: a FOCUS study analysis
por: Engels, Charla C., et al.
Publicado: (2016)

ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3
por: Ebbing, Eva A., et al.
Publicado: (2016)

The potential of combined mutation sequencing of plasma circulating cell‐free DNA and matched white blood cells for treatment response prediction
por: van der Leest, Paul, et al.
Publicado: (2020)

Uniform Noting for International Application of the Tumor-Stroma Ratio as an Easy Diagnostic Tool: Protocol for a Multicenter Prospective Cohort Study
por: Smit, Marloes, et al.
Publicado: (2019)

Receptor conversion in distant breast cancer metastases
por: Hoefnagel, Laurien DC, et al.
Publicado: (2010)

Aflatoxin B(1) Metabolism of Reared Alphitobius diaperinus in Different Life-Stages
por: Meijer, Nathan, et al.
Publicado: (2022)

Somatic mutations and copy number variations in breast cancers with heterogeneous HER2 amplification
por: Van Bockstal, Mieke R., et al.
Publicado: (2020)

Pathologic response of ductal carcinoma in situ to neoadjuvant systemic treatment in HER2-positive breast cancer
por: Groen, Emma J., et al.
Publicado: (2021)

Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain
por: van Rossum, Agnes GSH, et al.
Publicado: (2005)

Tumor stroma as contributing factor in the lymph node metastases process?
por: Mesker, Wilma E., et al.
Publicado: (2019)

e-Learning for Instruction and to Improve Reproducibility of Scoring Tumor-Stroma Ratio in Colon Carcinoma: Performance and Reproducibility Assessment in the UNITED Study
por: Smit, Marloes A, et al.
Publicado: (2021)

Tumour-stroma ratio outperforms tumour budding as biomarker in colon cancer: a cohort study
por: Smit, Marloes A., et al.
Publicado: (2021)

Efficacy of high-dose alkylating chemotherapy in the adjuvant treatment of HER2/neu-negative primary breast cancer: update of the Dutch randomized trial
por: Rodenhuis, S, et al.
Publicado: (2005)

Expert opinion as priors for random effects in Bayesian prediction models: Subclinical ketosis in dairy cows as an example
por: Ni, Haifang, et al.
Publicado: (2021)

The influence of micrometastases on prognosis and survival in stage I-II colon cancer patients: the Enroute⊕ Study
por: Lips, Daniel J, et al.
Publicado: (2011)

Deep (phospho)proteomics profiling of pre- treatment needle biopsies identifies signatures of treatment resistance in HER2(+) breast cancer
por: Debets, Donna O., et al.
Publicado: (2023)

Clinical impact of different detection methods for disseminated tumor cells in bone marrow of patients undergoing surgical resection of colorectal liver metastases: a prospective follow-up study
por: Vogelaar, F Jeroen, et al.
Publicado: (2010)

Increased assessment of HER2 in metastatic gastroesophageal cancer patients: a nationwide population-based cohort study
por: Dijksterhuis, Willemieke P. M., et al.
Publicado: (2020)

Frames and counter-frames giving meaning to palliative care and euthanasia in the Netherlands
por: Van Gorp, Baldwin, et al.
Publicado: (2021)

Prognostic value of breast MRI characteristics before and during neoadjuvant endocrine therapy in patients with ER+/HER2- breast cancer
por: Ragusi, Max AA, et al.
Publicado: (2021)

Gene-expression of metastasized versus non-metastasized primary head and neck squamous cell carcinomas: A pathway-based analysis
por: Hensen, Erik F, et al.
Publicado: (2008)

HER2 Status in High-Risk Endometrial Cancers (PORTEC-3): Relationship with Histotype, Molecular Classification, and Clinical Outcomes
por: Vermij, Lisa, et al.
Publicado: (2020)

Genomic patterns resembling BRCA1- and BRCA2-mutated breast cancers predict benefit of intensified carboplatin-based chemotherapy
por: Vollebergh, Marieke A, et al.
Publicado: (2014)

Cortactin overexpression results in sustained epidermal growth factor receptor signaling by preventing ligand-induced receptor degradation in human carcinoma cells
por: van Rossum, Agnes GSH, et al.
Publicado: (2005)

Survival is associated with complete response on MRI after neoadjuvant chemotherapy in ER-positive HER2-negative breast cancer
por: Loo, Claudette E., et al.
Publicado: (2016)

Efficacy of neoadjuvant treatment with or without pertuzumab in patients with stage II and III HER2-positive breast cancer: a nationwide cohort analysis of pathologic response and 5-year survival
por: van der Voort, Anna, et al.
Publicado: (2022)

Estrogen-related receptor alpha drives mitochondrial biogenesis and resistance to neoadjuvant chemoradiation in esophageal cancer
por: Dings, Mark P.G., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bj24d27vafr9fkvofk7rl89l87