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Paracrine interactions between primary human macrophages and human fibroblasts enhance murine mammary gland humanization in vivo

INTRODUCTION: Macrophages comprise an essential component of the mammary microenvironment necessary for normal gland development. However, there is no viable in vivo model to study their role in normal human breast function. We hypothesized that adding primary human macrophages to the murine mammary...

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Detalles Bibliográficos
Autores principales: Fleming, Jodie M, Miller, Tyler C, Kidacki, Michal, Ginsburg, Erika, Stuelten, Christina H, Stewart, Delisha A, Troester, Melissa A, Vonderhaar, Barbara K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446360/
https://www.ncbi.nlm.nih.gov/pubmed/22731827
http://dx.doi.org/10.1186/bcr3215

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