Protein tyrosine phosphatase Meg2 dephosphorylates signal transducer and activator of transcription 3 and suppresses tumor growth in breast cancer

INTRODUCTION: Signal transducer and activator of transcription 3 (STAT3) is over-activated or phosphorylated in breast cancers. The hyper-phosphorylation of STAT3 was attributed to either up-regulated phosphorylation by several tyrosine-kinases or down-regulated activity of phosphatases. Although se...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Fuqin, Ren, Fangli, Rong, Yu, Wang, Yangmeng, Geng, Yongtao, Wang, Yinyin, Feng, Mengyao, Ju, Yanfang, Li, Yi, Zhao, Zhizhuang J, Meng, Kun, Chang, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446372/
https://www.ncbi.nlm.nih.gov/pubmed/22394684
http://dx.doi.org/10.1186/bcr3134

Ejemplares similares

Ejemplares similares