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Effects of cyclin D(1 )gene amplification and protein expression on time to recurrence in postmenopausal breast cancer patients treated with anastrozole or tamoxifen: a TransATAC study
INTRODUCTION: Gene amplification of CCND1 is observed in a subgroup of breast cancers with poor prognosis, whereas overexpression of the protein cyclin D(1 )has been linked to both worse and better clinical outcome. CCND1 amplification and protein overexpression have also been associated with resist...
Autores principales: | Lundgren, Katja, Brown, Matthew, Pineda, Silvia, Cuzick, Jack, Salter, Janine, Zabaglo, Lila, Howell, Anthony, Dowsett, Mitch, Landberg, Göran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446392/ https://www.ncbi.nlm.nih.gov/pubmed/22475046 http://dx.doi.org/10.1186/bcr3161 |
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