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miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4

INTRODUCTION: miR-146a is one of the first identified miRNAs expressed differentially in osteoarthritis (OA) cartilage. However, the role it plays in OA pathogenesis is not clear. The aim of this study is to identify a molecular target of miR-146a, thereby elucidating its function in chondrocytes du...

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Detalles Bibliográficos
Autores principales:	Li, Jing, Huang, Jingang, Dai, Liming, Yu, Degang, Chen, Qian, Zhang, Xiaoling, Dai, Kerong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446449/ https://www.ncbi.nlm.nih.gov/pubmed/22507670 http://dx.doi.org/10.1186/ar3798

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