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Statins accelerate the onset of collagen type II-induced arthritis in mice
INTRODUCTION: Statins (hydroxymethylglutaryl coenzyme A reductase inhibitors) are effective in reducing the risk of cardiovascular morbidity and mortality in patients with hyperlipidemia, hypertension, or type II diabetes. Next to their cholesterol-lowering activity, statins have immunomodulatory pr...
Autores principales: | Vandebriel, Rob J, De Jong, Hilda JI, Gremmer, Eric R, Klungel, Olaf H, Tervaert, Jan-Willem Cohen, Slob, Wout, Van Der Laan, Jan Willem, Van Loveren, Henk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446464/ https://www.ncbi.nlm.nih.gov/pubmed/22537858 http://dx.doi.org/10.1186/ar3814 |
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