Cargando…

Interleukin-6 regulates anti-arthritic effect of methotrexate via reduction of SLC19A1 expression in a mouse arthritis model

INTRODUCTION: Methotrexate (MTX) enters cells via the reduced folate carrier SLC19A1, suggesting that SLC19A1 is associated with the efficacy of MTX. We here examined the relationship between the efficacy of MTX and the expression of SLC19A1 in glucose 6-phosphate isomerase (GPI)-induced arthritis....

Descripción completa

Detalles Bibliográficos
Autores principales:	Hashizume, Misato, Yoshida, Hiroto, Tanaka, Keisuke, Suzuki, Miho, Matsumoto, Isao, Sumida, Takayuki, Mihara, Masahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446470/ https://www.ncbi.nlm.nih.gov/pubmed/22546471 http://dx.doi.org/10.1186/ar3821

Ejemplares similares

The Roles of Interleukin-6 in the Pathogenesis of Rheumatoid Arthritis
por: Hashizume, Misato, et al.
Publicado: (2011)

Specific Increase in Joint Neutrophil Extracellular Traps and Its Relation to Interleukin 6 in Autoimmune Arthritis
por: Ohyama, Ayako, et al.
Publicado: (2021)

Review: Transcriptional Regulation of CD4+ T Cell Differentiation in Experimentally Induced Arthritis and Rheumatoid Arthritis
por: Kondo, Yuya, et al.
Publicado: (2018)

TIARP attenuates autoantibody-mediated arthritis via the suppression of neutrophil migration by reducing CXCL2/CXCR2 and IL-6 expression
por: Inoue, Asuka, et al.
Publicado: (2016)

Phytochemical and In-Vivo Anti-Arthritic Significance of Aloe thraskii Baker in Combined Therapy with Methotrexate in Adjuvant-Induced Arthritis in Rats
por: Kamal, Rania M., et al.
Publicado: (2021)

Crocus sativus L. Extract (Saffron) Effectively Reduces Arthritic and Inflammatory Parameters in Monotherapy and in Combination with Methotrexate in Adjuvant Arthritis
por: Chrastina, Martin, et al.
Publicado: (2023)

Therapeutic effects of antibodies to tumor necrosis factor-α, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis
por: Matsumoto, Isao, et al.
Publicado: (2008)

Tocilizumab, a humanized anti-interleukin-6 receptor antibody, for treatment of rheumatoid arthritis
por: Mihara, Masahiko, et al.
Publicado: (2011)

Glabridin Plays Dual Action to Augment the Efficacy and Attenuate the Hepatotoxicity of Methotrexate in Arthritic Rats
por: Dogra, Ashish, et al.
Publicado: (2022)

Interleukin 6 and Rheumatoid Arthritis
por: Yoshida, Yuji, et al.
Publicado: (2014)

Tumor necrosis factor α-induced adipose-related protein expression in experimental arthritis and in rheumatoid arthritis
por: Inoue, Asuka, et al.
Publicado: (2009)

Arthritis and pain. Current approaches in the treatment of arthritic pain
por: Kidd, Bruce L, et al.
Publicado: (2007)

Effect of climatic environment on immunological features of rheumatoid arthritis
por: Kondo, Yuya, et al.
Publicado: (2023)

Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis
por: Iwanami, Keiichi, et al.
Publicado: (2008)

T-bet represses collagen-induced arthritis by suppressing Th17 lineage commitment through inhibition of RORγt expression and function
por: Shimizu, Masaru, et al.
Publicado: (2021)

Nivolumab for Methotrexate-associated Classic Hodgkin's Lymphoma in a Rheumatoid Arthritis Patient
por: Tanaka, Keisuke, et al.
Publicado: (2019)

Discriminating phenotypic signatures identified for tocilizumab, adalimumab, and tofacitinib monotherapy and their combinations with methotrexate
por: O’Mahony, Alison, et al.
Publicado: (2018)

Efficacy of mizoribine pulse therapy in patients with rheumatoid arthritis who show a reduced or insufficient response to infliximab
por: Horikoshi, Masanobu, et al.
Publicado: (2009)

Anti-Arthritic Effects of Magnolol in Human Interleukin 1β-Stimulated Fibroblast-Like Synoviocytes and in a Rat Arthritis Model
por: Wang, Jyh-Horng, et al.
Publicado: (2012)

Anti-Arthritic Effect of Chebulanin on Collagen-Induced Arthritis in Mice
por: Zhao, Yinglan, et al.
Publicado: (2015)

Arthritic role of Porphyromonas gingivalis in collagen-induced arthritis mice
por: Jung, Hyerin, et al.
Publicado: (2017)

Arthritic Microenvironment Actuated Nanomotors for Active Rheumatoid Arthritis Therapy
por: Xu, Cong, et al.
Publicado: (2022)

Peptidylarginine deiminase type 4 deficiency reduced arthritis severity in a glucose-6-phosphate isomerase-induced arthritis model
por: Seri, Yu, et al.
Publicado: (2015)

Involvement of RORγt-overexpressing T cells in the development of autoimmune arthritis in mice
por: Kondo, Yuya, et al.
Publicado: (2015)

The temporomandibular joint in juvenile idiopathic arthritis: frequently used and frequently arthritic
por: Ringold, Sarah, et al.
Publicado: (2009)

Identification of novel biomarker as citrullinated inter-alpha-trypsin inhibitor heavy chain 4, specifically increased in sera with experimental and rheumatoid arthritis
por: Kawaguchi, Hoshimi, et al.
Publicado: (2018)

Nano Methotrexate versus Methotrexate in Targeting Rheumatoid Arthritis
por: Salem, Heba F., et al.
Publicado: (2022)

Lymphoproliferative disorder risk after methotrexate treatment for rheumatoid arthritis
por: Tanaka, Keisuke, et al.
Publicado: (2023)

Activation of Invariant NKT Cells with Glycolipid Ligand α-Galactosylceramide Ameliorates Glucose-6-Phosphate Isomerase Peptide-Induced Arthritis
por: Horikoshi, Masanobu, et al.
Publicado: (2012)

Baseline Serum Osteopontin Levels Predict the Clinical Effectiveness of Tocilizumab but Not Infliximab in Biologic-Naïve Patients with Rheumatoid Arthritis: A Single-Center Prospective Study at 1 Year (the Keio First-Bio Cohort Study)
por: Izumi, Keisuke, et al.
Publicado: (2015)

Anti-Arthritic Effect of Garcinol Enriched Fraction Against Adjuvant Induced Arthritis
por: Warriar, Purnima, et al.
Publicado: (2019)

Anabasis articulata exerts an anti-arthritic effect on adjuvant-induced arthritis in rats
por: Abdulhusain, Zaid Hamzah, et al.
Publicado: (2022)

Correction: Baseline Serum Osteopontin Levels Predict the Clinical Effectiveness of Tocilizumab but Not Infliximab in Biologic-Naïve Patients with Rheumatoid Arthritis: A Single-Center Prospective Study at 1 Year (the Keio First-Bio Cohort Study)
por: Izumi, Keisuke, et al.
Publicado: (2016)

Methotrexate alone and methotrexate combined with etanercept in treatment of rheumatoid arthritis
por: Rexhepi, Sylejman, et al.
Publicado: (2012)

Achieving sustained minimal disease activity with methotrexate in early interleukin 23-driven early psoriatic arthritis
por: den Braanker, Hannah, et al.
Publicado: (2020)

Pulmonary Intravascular Large B-cell Lymphoma in a Patient Administered Methotrexate for Rheumatoid Arthritis
por: Iwami, Eri, et al.
Publicado: (2019)

Anti-Arthritic Activity of Premna serratifolia Linn., Wood against Adjuvant Induced Arthritis
por: Rajendran, Rekha, et al.
Publicado: (2010)

Serum proteomic analysis of the anti-arthritic effects of sinomenine on rats with collagen-induced arthritis
por: Qian, Xin, et al.
Publicado: (2018)

Targeted apoptosis of macrophages and osteoclasts in arthritic joints is effective against advanced inflammatory arthritis
por: Deng, Caifeng, et al.
Publicado: (2021)

Anti-Arthritic and Anti-Inflammatory Effects of Andaliman Extract and Nanoandaliman in Inflammatory Arthritic Mice
por: Setiadi, Anselmus Yakobus Lukita Adiandra, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_q9nnq9q8gkbgo859d4d8qmbfa5