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Treatment with the arginase inhibitor N(w)-hydroxy-nor-L-arginine restores endothelial function in rat adjuvant-induced arthritis

INTRODUCTION: Endothelial dysfunction (ED) participates to atherogenesis associated to rheumatoid arthritis. We recently reported increased arginase activity/expression in vessels from adjuvant-induced arthritis (AIA) rats. In the present study, we investigated the effects of a curative treatment wi...

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Detalles Bibliográficos
Autores principales: Prati, Clément, Berthelot, Alain, Kantelip, Bernadette, Wendling, Daniel, Demougeot, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446511/
https://www.ncbi.nlm.nih.gov/pubmed/22647483
http://dx.doi.org/10.1186/ar3860