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Treatment with the arginase inhibitor N(w)-hydroxy-nor-L-arginine restores endothelial function in rat adjuvant-induced arthritis
INTRODUCTION: Endothelial dysfunction (ED) participates to atherogenesis associated to rheumatoid arthritis. We recently reported increased arginase activity/expression in vessels from adjuvant-induced arthritis (AIA) rats. In the present study, we investigated the effects of a curative treatment wi...
Autores principales: | Prati, Clément, Berthelot, Alain, Kantelip, Bernadette, Wendling, Daniel, Demougeot, Céline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446511/ https://www.ncbi.nlm.nih.gov/pubmed/22647483 http://dx.doi.org/10.1186/ar3860 |
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