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Dermatologic Toxicities from Monoclonal Antibodies and Tyrosine Kinase Inhibitors against EGFR: Pathophysiology and Management

Epidermal growth factor receptor (EGFR) inhibition has now been well established as an effective treatment for various cancers. The EGFR belongs to the ErbB family of tyrosine kinase receptors which regulate tumor cell differentiation, survival and proliferation. Activation of EGFR drives tumorigene...

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Detalles Bibliográficos
Autores principales:	Abdullah, Shaad E., Haigentz, Missak, Piperdi, Bilal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446637/ https://www.ncbi.nlm.nih.gov/pubmed/22997576 http://dx.doi.org/10.1155/2012/351210

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