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Coinhibitory Molecules in Autoimmune Diseases

Coinhibitory molecules such as CTLA-4, PD-1 and BTLA negatively regulate immune responses. Multiple studies indicate that the deficiency or mutation of coinhibitory molecules leads to the development of autoimmune diseases in mice and humans, indicating that the negative signals from coinhibitory mo...

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Detalles Bibliográficos
Autores principales:	Watanabe, Norihiko, Nakajima, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446788/ https://www.ncbi.nlm.nih.gov/pubmed/22997525 http://dx.doi.org/10.1155/2012/269756

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