Cargando…

Indomethacin-loaded lipid-core nanocapsules reduce the damage triggered by Aβ1-42 in Alzheimer’s disease models

Neuroinflammation, characterized by the accumulation of activated microglia and reactive astrocytes, is believed to modulate the development and/or progression of Alzheimer’s disease (AD). Epidemiological studies suggesting that nonsteroidal anti-inflammatory drugs decrease the risk of developing AD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bernardi, Andressa, Frozza, Rudimar L, Meneghetti, André, Hoppe, Juliana B, Battastini, Ana Maria O, Pohlmann, Adriana R, Guterres, Sílvia S, Salbego, Christianne G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446842/ https://www.ncbi.nlm.nih.gov/pubmed/23028221 http://dx.doi.org/10.2147/IJN.S35333

Ejemplares similares

The antiproliferative effect of indomethacin-loaded lipid-core nanocapsules in glioma cells is mediated by cell cycle regulation, differentiation, and the inhibition of survival pathways
por: Bernardi, Andressa, et al.
Publicado: (2013)

Labeling the oily core of nanocapsules and lipid-core nanocapsules with a triglyceride conjugated to a fluorescent dye as a strategy to particle tracking in biological studies
por: Fiel, Luana Almeida, et al.
Publicado: (2014)

Resveratrol-Loaded Lipid-Core Nanocapsules Modulate Acute Lung Inflammation and Oxidative Imbalance Induced by LPS in Mice
por: de Oliveira, Maria Talita Pacheco, et al.
Publicado: (2021)

α-bisabolol-loaded lipid-core nanocapsules reduce lipopolysaccharide-induced pulmonary inflammation in mice
por: D’Almeida, Ana Paula L, et al.
Publicado: (2017)

Orally delivered resveratrol-loaded lipid-core nanocapsules ameliorate LPS-induced acute lung injury via the ERK and PI3K/Akt pathways
por: de Oliveira, Maria Talita Pacheco, et al.
Publicado: (2019)

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication
por: Silva, Ygor Parladore, et al.
Publicado: (2020)

Data of characterization and related assays of lipid-core nanocapsule formulations and their hydrolysis mechanism
por: Calgaroto, Selma, et al.
Publicado: (2018)

Methotrexate-loaded lipid-core nanocapsules are highly effective in the control of inflammation in synovial cells and a chronic arthritis model
por: Boechat, Antônio Luiz, et al.
Publicado: (2015)

Polymeric Nanoparticles, Nanospheres and Nanocapsules, for Cutaneous Applications
por: Guterres, Sílvia S., et al.
Publicado: (2007)

Mechanisms of the effectiveness of poly(ε-caprolactone) lipid-core nanocapsules loaded with methotrexate on glioblastoma multiforme treatment
por: Pereira, Natalia Rubio Claret, et al.
Publicado: (2018)

Melatonin-loaded lipid-core nanocapsules protect against lipid peroxidation caused by paraquat through increased SOD expression in Caenorhabditis elegans
por: Charão, Mariele F., et al.
Publicado: (2019)

Oral Treatment of Spontaneously Hypertensive Rats with Captopril-Surface Functionalized Furosemide-Loaded Multi-Wall Lipid-Core Nanocapsules
por: Michalowski, Cecilia B., et al.
Publicado: (2020)

Effects of Two Types of Melatonin-Loaded Nanocapsules with Distinct Supramolecular Structures: Polymeric (NC) and Lipid-Core Nanocapsules (LNC) on Bovine Embryo Culture Model
por: Komninou, Eliza Rossi, et al.
Publicado: (2016)

Hesperetin-loaded lipid-core nanocapsules in polyamide: a new textile formulation for topical drug delivery
por: Menezes, Paula dos Passos, et al.
Publicado: (2017)

Arginylglycylaspartic Acid-Surface-Functionalized Doxorubicin-Loaded Lipid-Core Nanocapsules as a Strategy to Target Alpha(V) Beta(3) Integrin Expressed on Tumor Cells
por: Antonow, Michelli B., et al.
Publicado: (2017)

Anti-Inflammatory Effects of Resveratrol: Mechanistic Insights
por: de Sá Coutinho, Diego, et al.
Publicado: (2018)

Role of poly(ε-caprolactone) lipid-core nanocapsules on melanoma–neutrophil crosstalk
por: Drewes, Carine C, et al.
Publicado: (2017)

Novel therapeutic mechanisms determine the effectiveness of lipid-core nanocapsules on melanoma models
por: Drewes, Carine C, et al.
Publicado: (2016)

Caenorhabditis elegans as an alternative in vivo model to determine oral uptake, nanotoxicity, and efficacy of melatonin-loaded lipid-core nanocapsules on paraquat damage
por: Charão, Mariele Feiffer, et al.
Publicado: (2015)

Lapatinib-Loaded Nanocapsules Enhances Antitumoral Effect in Human Bladder Cancer Cell
por: Buss, Julieti Huch, et al.
Publicado: (2019)

Triclosan resistance reversion by encapsulation in chitosan-coated-nanocapsule containing α-bisabolol as core: development of wound dressing
por: De Marchi, João Guilherme B, et al.
Publicado: (2017)

Methotrexate diethyl ester-loaded lipid-core nanocapsules in aqueous solution increased antineoplastic effects in resistant breast cancer cell line
por: Yurgel, Virginia C, et al.
Publicado: (2014)

The Anti-Arthritic Activity of Diclofenac Lipid-Core Nanocapsules: Stereological Analysis Showing More Protection of Deep Joint Components
por: Ureña, Nathalie Marte, et al.
Publicado: (2023)

Hydrogels containing redispersible spray-dried melatonin-loaded nanocapsules: a formulation for transdermal-controlled delivery
por: Hoffmeister, Cristiane RD, et al.
Publicado: (2012)

A set of synthetic data, antibacterial evaluation and bacterial interaction with lipid-core nanocapsules containing fusidic acid
por: Cé, Rodrigo, et al.
Publicado: (2021)

Chitosan gel containing polymeric nanocapsules: a new formulation for vaginal drug delivery
por: Frank, Luiza A, et al.
Publicado: (2014)

Enhanced and Selective Antiproliferative Activity of Methotrexate-Functionalized-Nanocapsules to Human Breast Cancer Cells (MCF-7)
por: de Oliveira, Catiúscia P., et al.
Publicado: (2018)

Toltrazuril-Loaded Polymeric Nanocapsules as a Promising Approach for the Preventive Control of Coccidiosis in Poultry
por: Baron, Lana Flávia, et al.
Publicado: (2022)

Phosphatidylinositol 3-Kinase/AKT Pathway Inhibition by Doxazosin Promotes Glioblastoma Cells Death, Upregulation of p53 and Triggers Low Neurotoxicity
por: Gaelzer, Mariana Maier, et al.
Publicado: (2016)

Iron-Loaded Magnetic Nanocapsules for pH-Triggered Drug Release and MRI Imaging
por: Chen, Hongyu, et al.
Publicado: (2014)

Challenges for Alzheimer's Disease Therapy: Insights from Novel Mechanisms Beyond Memory Defects
por: Frozza, Rudimar L., et al.
Publicado: (2018)

Ifosfamide-loaded lipid-core-nanocapsules to increase the anticancer efficacy in MG63 osteosarcoma cells
por: Wang, Sheng-Qun, et al.
Publicado: (2018)

Pequi (Caryocar brasiliense Cambess)-Loaded Nanoemulsion, Orally Delivered, Modulates Inflammation in LPS-Induced Acute Lung Injury in Mice
por: de Sá Coutinho, Diego, et al.
Publicado: (2020)

Design of indomethacin-loaded nanoparticles: effect of polymer matrix and surfactant
por: Dupeyrón, Danay, et al.
Publicado: (2013)

Trazodone Loaded Lipid Core Poly (ε-caprolactone) Nanocapsules: Development, Characterization and in Vivo Antidepressant Effect Evaluation
por: Elhesaisy, Nahla, et al.
Publicado: (2020)

Characterization and In Vitro and In Vivo Evaluation of Tacrolimus-Loaded Poly(ε-Caprolactone) Nanocapsules for the Management of Atopic Dermatitis
por: Camargo, Guilherme dos Anjos, et al.
Publicado: (2021)

Formulation of essential oil-loaded chitosan–alginate nanocapsules
por: Natrajan, Dheebika, et al.
Publicado: (2015)

Preparation and In Vivo Evaluation of Indomethacin Loaded True Nanoemulsions
por: Shakeel, Faiyaz, et al.
Publicado: (2010)

Development and characterization of sorafenib-loaded lipid nanocapsules for the treatment of glioblastoma
por: Clavreul, Anne, et al.
Publicado: (2018)

Thymoquinone-loaded lipid nanocapsules with promising anticancer activity for colorectal cancer
por: Selmi, Mouna, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_o7bvkk3v4g1klkfge97vh988sg