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Identification of Early Biomarkers during Acetaminophen-Induced Hepatotoxicity by Fourier Transform Infrared Microspectroscopy
Acetaminophen is a widely prescribed drug used to relieve pain and fever; however, it is a leading cause of drug-induced liver injury and a burden on public healthcare. In this study, hepatotoxicity in mice post oral dosing of acetaminophen was investigated using liver and sera samples with Fourier...
Autores principales: | Gautam, Rekha, Chandrasekar, Bhagawat, Deobagkar-Lele, Mukta, Rakshit, Srabanti, Kumar B. N., Vinay, Umapathy, Siva, Nandi, Dipankar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446881/ https://www.ncbi.nlm.nih.gov/pubmed/23029070 http://dx.doi.org/10.1371/journal.pone.0045521 |
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