Decorin Protein Core Affects the Global Gene Expression Profile of the Tumor Microenvironment in a Triple-Negative Orthotopic Breast Carcinoma Xenograft Model

Decorin, a member of the small leucine-rich proteoglycan gene family, exists and functions wholly within the tumor microenvironment to suppress tumorigenesis by directly targeting and antagonizing multiple receptor tyrosine kinases, such as the EGFR and Met. This leads to potent and sustained signal...

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Detalles Bibliográficos
Autores principales: Buraschi, Simone, Neill, Thomas, Owens, Rick T., Iniguez, Leonardo A., Purkins, George, Vadigepalli, Rajanikanth, Evans, Barry, Schaefer, Liliana, Peiper, Stephen C., Wang, Zi-Xuan, Iozzo, Renato V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446891/
https://www.ncbi.nlm.nih.gov/pubmed/23029096
http://dx.doi.org/10.1371/journal.pone.0045559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446891/
https://www.ncbi.nlm.nih.gov/pubmed/23029096
http://dx.doi.org/10.1371/journal.pone.0045559

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