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Autophagy Mediates the Delivery of Thrombogenic Tissue Factor to Neutrophil Extracellular Traps in Human Sepsis

BACKGROUND: Sepsis is associated with systemic inflammatory responses and induction of coagulation system. Neutrophil extracellular traps (NETs) constitute an antimicrobial mechanism, recently implicated in thrombosis via platelet entrapment and aggregation. METHODOLOGY/PRINCIPAL FINDINGS: In this s...

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Detalles Bibliográficos
Autores principales: Kambas, Konstantinos, Mitroulis, Ioannis, Apostolidou, Eirini, Girod, Andreas, Chrysanthopoulou, Akrivi, Pneumatikos, Ioannis, Skendros, Panagiotis, Kourtzelis, Ioannis, Koffa, Maria, Kotsianidis, Ioannis, Ritis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446899/
https://www.ncbi.nlm.nih.gov/pubmed/23029002
http://dx.doi.org/10.1371/journal.pone.0045427