Cargando…

Association of β-defensin copy number and psoriasis in three cohorts of European origin

A single previous study has demonstrated significant association of psoriasis with copy number of beta-defensin genes, using DNA from psoriasis cases and controls from Nijmegen and Erlangen. In this study we attempted to replicate that finding in larger new cohorts from Erlangen (N = 2017) and Michi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stuart, Philip E, Hüffmeier, Ulrike, Nair, Rajan P, Palla, Raquel, Tejasvi, Trilokraj, Schalkwijk, Joost, Elder, James T, Reis, Andre, Armour, John AL
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447111/ https://www.ncbi.nlm.nih.gov/pubmed/22739795 http://dx.doi.org/10.1038/jid.2012.191

Ejemplares similares

TNFAIP3 Gene Polymorphisms Are Associated with Response to TNF Blockade in Psoriasis
por: Tejasvi, Trilokraj, et al.
Publicado: (2011)

Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats
por: Armour, John A. L., et al.
Publicado: (2007)

Beta-defensin genomic copy number is not a modifier locus for cystic fibrosis
por: Hollox, Edward J, et al.
Publicado: (2005)

Accurate measurement of gene copy number for human alpha-defensin DEFA1A3
por: Khan, Fayeza F, et al.
Publicado: (2013)

Accuracy and differential bias in copy number measurement of CCL3L1 in association studies with three auto-immune disorders
por: Carpenter, Danielle, et al.
Publicado: (2011)

Large-Scale Imputation of KIR Copy Number and HLA Alleles in North American and European Psoriasis Case-Control Cohorts Reveals Association of Inhibitory KIR2DL2 With Psoriasis
por: Ahn, Richard, et al.
Publicado: (2021)

Transethnic analysis of psoriasis susceptibility in South Asians and Europeans enhances fine mapping in the MHC and genome wide
por: Stuart, Philip E., et al.
Publicado: (2021)

Copy Number Variation of the Beta-Defensin Genes in Europeans: No Supporting Evidence for Association with Lung Function, Chronic Obstructive Pulmonary Disease or Asthma
por: Wain, Louise V., et al.
Publicado: (2014)

Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms
por: Li, Bingshan, et al.
Publicado: (2014)

β-Defensin-2 Protein Is a Serum Biomarker for Disease Activity in Psoriasis and Reaches Biologically Relevant Concentrations in Lesional Skin
por: Jansen, Patrick A. M., et al.
Publicado: (2009)

Determination of Beta-Defensin Genomic Copy Number in Different Populations: A Comparison of Three Methods
por: Fode, Peder, et al.
Publicado: (2011)

Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations
por: Hughes, Timothy, et al.
Publicado: (2020)

Genome-wide association and targeted analysis of copy number variants with psoriatic arthritis in German patients
por: Uebe, Steffen, et al.
Publicado: (2017)

Copy Number Variation across European Populations
por: Chen, Wanting, et al.
Publicado: (2011)

An Evolutionary History of Defensins: A Role for Copy Number Variation in Maximizing Host Innate and Adaptive Immune Responses
por: Machado, Lee R., et al.
Publicado: (2015)

Directional and balancing selection in human beta-defensins
por: Hollox, Edward J, et al.
Publicado: (2008)

Genome-wide association analysis identifies three psoriasis susceptibility loci
por: Stuart, Philip E., et al.
Publicado: (2010)

Functional effects of CCL3L1 copy number
por: Carpenter, Danielle, et al.
Publicado: (2012)

Novel origins of copy number variation in the dog genome
por: Berglund, Jonas, et al.
Publicado: (2012)

The impact and origin of copy number variations in the Oryza species
por: Bai, Zetao, et al.
Publicado: (2016)

Fine Mapping Major Histocompatibility Complex Associations in Psoriasis and Its Clinical Subtypes
por: Okada, Yukinori, et al.
Publicado: (2014)

Narrowing down the distal border of the copy number variable beta-defensin gene cluster on human 8p23
por: Taudien, Stefan, et al.
Publicado: (2014)

Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis
por: Taudien, Stefan, et al.
Publicado: (2012)

Evidence of Convergent Evolution in Humans and Macaques Supports an Adaptive Role for Copy Number Variation of the β-Defensin-2 Gene
por: Ottolini, Barbara, et al.
Publicado: (2014)

Dermoscopy of Aplasia Cutis Congenita: A Case Report and Review of the Literature
por: Neelam, Rasna, et al.
Publicado: (2021)

A Worldwide Analysis of Beta-Defensin Copy Number Variation Suggests Recent Selection of a High-Expressing DEFB103 Gene Copy in East Asia
por: Hardwick, Robert J, et al.
Publicado: (2011)

CCL3L1 copy number and susceptibility to malaria
por: Carpenter, Danielle, et al.
Publicado: (2012)

A Single SNP Surrogate for Genotyping HLA-C*06:02 in Diverse Populations
por: Stuart, Philip E., et al.
Publicado: (2014)

Quadruplex MAPH: improvement of throughput in high-resolution copy number screening
por: Tyson, Jess, et al.
Publicado: (2009)

Haplotyping and copy number estimation of the highly polymorphic human beta-defensin locus on 8p23 by 454 amplicon sequencing
por: Taudien, Stefan, et al.
Publicado: (2010)

Development and Evaluation of a Droplet Digital PCR Assay for 8p23 β-Defensin Cluster Copy Number Determination
por: Wen, Tingting, et al.
Publicado: (2021)

Leukocyte mitochondrial DNA copy number is a potential non-invasive biomarker for psoriasis
por: Alwehaidah, Materah Salem, et al.
Publicado: (2022)

Human beta defensin (HBD) gene copy number affects HBD2 protein levels: impact on cervical bactericidal immunity in pregnancy
por: James, Catherine P., et al.
Publicado: (2018)

Cutaneous T‐cell lymphomas: 2023 update on diagnosis, risk‐stratification, and management
por: Hristov, Alexandra C., et al.
Publicado: (2022)

Microarray MAPH: accurate array-based detection of relative copy number in genomic DNA
por: Gibbons, Brian, et al.
Publicado: (2006)

Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients
por: Patrick, Matthew T., et al.
Publicado: (2018)

Distribution and Functionality of Copy Number Variation across European Cattle Populations
por: Upadhyay, Maulik, et al.
Publicado: (2017)

Systematic biases in DNA copy number originate from isolation procedures
por: van Heesch, Sebastiaan, et al.
Publicado: (2013)

Origins and Long-Term Patterns of Copy-Number Variation in Rhesus Macaques
por: Thomas, Gregg W C, et al.
Publicado: (2020)

Comprehensive assessment of sequence variation within the copy number variable defensin cluster on 8p23 by target enriched in-depth 454 sequencing
por: Taudien, Stefan, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_fhlvl6v5dnr1300vkr12m0sopa