The Impact of Osteopontin Gene Variations on Multiple Sclerosis Development and Progression

Osteopontin is a proinflammatory molecule, modulating TH1 and TH17 responses. Several reports suggest its involvement in multiple sclerosis (MS) pathogenesis. We previously reported that OPN gene variations at the 3′ end are a predisposing factor for MS development and evolution. In this paper, we e...

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Detalles Bibliográficos
Autores principales: Comi, Cristoforo, Cappellano, Giuseppe, Chiocchetti, Annalisa, Orilieri, Elisabetta, Buttini, Sara, Ghezzi, Laura, Galimberti, Daniela, Guerini, Franca, Barizzone, Nadia, Perla, Franco, Leone, Maurizio, D'Alfonso, Sandra, Caputo, Domenico, Scarpini, Elio, Cantello, Roberto, Dianzani, Umberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447190/
https://www.ncbi.nlm.nih.gov/pubmed/23008732
http://dx.doi.org/10.1155/2012/212893

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