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The Mode of Pretransplant Dialysis Does Not Affect Postrenal Transplant Outcomes in African Americans

Background. In previous reports with a majority of Caucasian patients, peritoneal dialysis (PD) before kidney transplantation has been associated with poor outcomes and higher rates of graft thrombosis and infectious complications than hemodialysis (HD). We report our experience on the outcomes of p...

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Autores principales: Sharma, Amit, Teigeler, Todd L., Behnke, Martha, Cotterell, Adrian, Fisher, Robert, King, Anne, Gehr, Todd, Posner, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447363/
https://www.ncbi.nlm.nih.gov/pubmed/23008755
http://dx.doi.org/10.1155/2012/303596
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author Sharma, Amit
Teigeler, Todd L.
Behnke, Martha
Cotterell, Adrian
Fisher, Robert
King, Anne
Gehr, Todd
Posner, Marc
author_facet Sharma, Amit
Teigeler, Todd L.
Behnke, Martha
Cotterell, Adrian
Fisher, Robert
King, Anne
Gehr, Todd
Posner, Marc
author_sort Sharma, Amit
collection PubMed
description Background. In previous reports with a majority of Caucasian patients, peritoneal dialysis (PD) before kidney transplantation has been associated with poor outcomes and higher rates of graft thrombosis and infectious complications than hemodialysis (HD). We report our experience on the outcomes of prerenal transplant peritoneal dialysis in predominantly (73%) African American patient population. Methods. A retrospective data analysis of 401 kidney transplants performed at our center from 2000 to 2006 was performed. Adult recipients with at least three months of pretransplant HD or PD were included. Results. There were 339 patients on HD and 62 patients on PD. There was no difference in graft (P = 0.51) and patient survival (P = 0.52) at 1, 3, and 5-years. Patients on HD were more likely to experience delayed graft function than PD (38.8% versus 17.7%, P < 0.005). There was no difference in the incidence of vascular thrombosis or posttransplant infectious complications. When only the African American patients in the two groups were compared, there were no differences in graft or patient survival. Conclusions. Pretransplant peritoneal dialysis is associated with excellent patient and renal allograft outcomes in African Americans and does not predispose them to an increased risk of infectious or thrombotic complications.
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spelling pubmed-34473632012-09-24 The Mode of Pretransplant Dialysis Does Not Affect Postrenal Transplant Outcomes in African Americans Sharma, Amit Teigeler, Todd L. Behnke, Martha Cotterell, Adrian Fisher, Robert King, Anne Gehr, Todd Posner, Marc J Transplant Clinical Study Background. In previous reports with a majority of Caucasian patients, peritoneal dialysis (PD) before kidney transplantation has been associated with poor outcomes and higher rates of graft thrombosis and infectious complications than hemodialysis (HD). We report our experience on the outcomes of prerenal transplant peritoneal dialysis in predominantly (73%) African American patient population. Methods. A retrospective data analysis of 401 kidney transplants performed at our center from 2000 to 2006 was performed. Adult recipients with at least three months of pretransplant HD or PD were included. Results. There were 339 patients on HD and 62 patients on PD. There was no difference in graft (P = 0.51) and patient survival (P = 0.52) at 1, 3, and 5-years. Patients on HD were more likely to experience delayed graft function than PD (38.8% versus 17.7%, P < 0.005). There was no difference in the incidence of vascular thrombosis or posttransplant infectious complications. When only the African American patients in the two groups were compared, there were no differences in graft or patient survival. Conclusions. Pretransplant peritoneal dialysis is associated with excellent patient and renal allograft outcomes in African Americans and does not predispose them to an increased risk of infectious or thrombotic complications. Hindawi Publishing Corporation 2012 2012-09-12 /pmc/articles/PMC3447363/ /pubmed/23008755 http://dx.doi.org/10.1155/2012/303596 Text en Copyright © 2012 Amit Sharma et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Sharma, Amit
Teigeler, Todd L.
Behnke, Martha
Cotterell, Adrian
Fisher, Robert
King, Anne
Gehr, Todd
Posner, Marc
The Mode of Pretransplant Dialysis Does Not Affect Postrenal Transplant Outcomes in African Americans
title The Mode of Pretransplant Dialysis Does Not Affect Postrenal Transplant Outcomes in African Americans
title_full The Mode of Pretransplant Dialysis Does Not Affect Postrenal Transplant Outcomes in African Americans
title_fullStr The Mode of Pretransplant Dialysis Does Not Affect Postrenal Transplant Outcomes in African Americans
title_full_unstemmed The Mode of Pretransplant Dialysis Does Not Affect Postrenal Transplant Outcomes in African Americans
title_short The Mode of Pretransplant Dialysis Does Not Affect Postrenal Transplant Outcomes in African Americans
title_sort mode of pretransplant dialysis does not affect postrenal transplant outcomes in african americans
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447363/
https://www.ncbi.nlm.nih.gov/pubmed/23008755
http://dx.doi.org/10.1155/2012/303596
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