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Diagnostic Significance of Intracystic Nodules on MRI in Rathke's Cleft Cyst

Background and Purpose. To explore strategies for the diagnosis and treatment of Rathke's cleft cyst (RCC). Methods. The medical records of 24 patients with sellar RCC were retrospectively reviewed. Two patients had concomitant pituitary adenoma, 2 underwent transcranial surgery, and 22 underwe...

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Autores principales: Wang, Shou-sen, Xiao, De-yong, Yu, Ying-hao, Jing, Jun-jie, Zhao, Lin, Wang, Ru-mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447369/
https://www.ncbi.nlm.nih.gov/pubmed/23008711
http://dx.doi.org/10.1155/2012/958732
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author Wang, Shou-sen
Xiao, De-yong
Yu, Ying-hao
Jing, Jun-jie
Zhao, Lin
Wang, Ru-mi
author_facet Wang, Shou-sen
Xiao, De-yong
Yu, Ying-hao
Jing, Jun-jie
Zhao, Lin
Wang, Ru-mi
author_sort Wang, Shou-sen
collection PubMed
description Background and Purpose. To explore strategies for the diagnosis and treatment of Rathke's cleft cyst (RCC). Methods. The medical records of 24 patients with sellar RCC were retrospectively reviewed. Two patients had concomitant pituitary adenoma, 2 underwent transcranial surgery, and 22 underwent transsphenoidal surgery. The clinical features, especially the findings of intracystic nodules on MRI, were evaluated and compared with the pathological findings. Results. Preoperatively, only 2 patients were diagnosed with RCC or suspected RCC. Pre- and postoperative MRI images revealed 10 intracystic nodules in 9 (37.5%) patients. Two nodules had bull's eyelike changes. The signal intensity of the intracystic nodules varied on T1- and T2-weighted images. Not all nodules on T2-weighted images were visualized. Postoperative MRI revealed recurrence or residual lesion in 5 patients; none had new symptoms and a second surgery was not required. Conclusions. Identifying intracystic nodules is important in patients with sellar cystic lesions. Bull's eyelike change in an intracystic nodule on MRI, which is reported here for the first time, potentially might have value for confirming the diagnosis.
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spelling pubmed-34473692012-09-24 Diagnostic Significance of Intracystic Nodules on MRI in Rathke's Cleft Cyst Wang, Shou-sen Xiao, De-yong Yu, Ying-hao Jing, Jun-jie Zhao, Lin Wang, Ru-mi Int J Endocrinol Clinical Study Background and Purpose. To explore strategies for the diagnosis and treatment of Rathke's cleft cyst (RCC). Methods. The medical records of 24 patients with sellar RCC were retrospectively reviewed. Two patients had concomitant pituitary adenoma, 2 underwent transcranial surgery, and 22 underwent transsphenoidal surgery. The clinical features, especially the findings of intracystic nodules on MRI, were evaluated and compared with the pathological findings. Results. Preoperatively, only 2 patients were diagnosed with RCC or suspected RCC. Pre- and postoperative MRI images revealed 10 intracystic nodules in 9 (37.5%) patients. Two nodules had bull's eyelike changes. The signal intensity of the intracystic nodules varied on T1- and T2-weighted images. Not all nodules on T2-weighted images were visualized. Postoperative MRI revealed recurrence or residual lesion in 5 patients; none had new symptoms and a second surgery was not required. Conclusions. Identifying intracystic nodules is important in patients with sellar cystic lesions. Bull's eyelike change in an intracystic nodule on MRI, which is reported here for the first time, potentially might have value for confirming the diagnosis. Hindawi Publishing Corporation 2012 2012-09-12 /pmc/articles/PMC3447369/ /pubmed/23008711 http://dx.doi.org/10.1155/2012/958732 Text en Copyright © 2012 Shou-sen Wang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Wang, Shou-sen
Xiao, De-yong
Yu, Ying-hao
Jing, Jun-jie
Zhao, Lin
Wang, Ru-mi
Diagnostic Significance of Intracystic Nodules on MRI in Rathke's Cleft Cyst
title Diagnostic Significance of Intracystic Nodules on MRI in Rathke's Cleft Cyst
title_full Diagnostic Significance of Intracystic Nodules on MRI in Rathke's Cleft Cyst
title_fullStr Diagnostic Significance of Intracystic Nodules on MRI in Rathke's Cleft Cyst
title_full_unstemmed Diagnostic Significance of Intracystic Nodules on MRI in Rathke's Cleft Cyst
title_short Diagnostic Significance of Intracystic Nodules on MRI in Rathke's Cleft Cyst
title_sort diagnostic significance of intracystic nodules on mri in rathke's cleft cyst
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447369/
https://www.ncbi.nlm.nih.gov/pubmed/23008711
http://dx.doi.org/10.1155/2012/958732
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