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Glibenclamide Induces Collagen IV Catabolism in High Glucose-Stimulated Mesangial Cells

We have shown the full prevention of mesangial expansion in insulin-deficient diabetic rats by treatment with clinically-relevant dosages of glibenclamide (Glib). Studies in mesangial cells (MCs) also demonstrated reduction in the high glucose (HG)-induced accumulation of collagens, proposing that t...

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Detalles Bibliográficos
Autores principales:	Zhu, Liping, Cortes, Pedro, Hassett, Clare, Taube, David W., Yee, Jerry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447387/ https://www.ncbi.nlm.nih.gov/pubmed/23008698 http://dx.doi.org/10.1155/2012/183535

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