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Characterization of a 3D optrode array for infrared neural stimulation

This paper characterizes the Utah Slant Optrode Array (USOA) as a means to deliver infrared light deep into tissue. An undoped crystalline silicon (100) substrate was used to fabricate 10 × 10 arrays of optrodes with rows of varying lengths from 0.5 mm to 1.5 mm on a 400-μm pitch. Light delivery fro...

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Detalles Bibliográficos
Autores principales: Abaya, T.V.F., Diwekar, M., Blair, S., Tathireddy, P., Rieth, L., Clark, G.A., Solzbacher, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447562/
https://www.ncbi.nlm.nih.gov/pubmed/23024914
http://dx.doi.org/10.1364/BOE.3.002200
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author Abaya, T.V.F.
Diwekar, M.
Blair, S.
Tathireddy, P.
Rieth, L.
Clark, G.A.
Solzbacher, F.
author_facet Abaya, T.V.F.
Diwekar, M.
Blair, S.
Tathireddy, P.
Rieth, L.
Clark, G.A.
Solzbacher, F.
author_sort Abaya, T.V.F.
collection PubMed
description This paper characterizes the Utah Slant Optrode Array (USOA) as a means to deliver infrared light deep into tissue. An undoped crystalline silicon (100) substrate was used to fabricate 10 × 10 arrays of optrodes with rows of varying lengths from 0.5 mm to 1.5 mm on a 400-μm pitch. Light delivery from optical fibers and loss mechanisms through these Si optrodes were characterized, with the primary loss mechanisms being Fresnel reflection, coupling, radiation losses from the tapered shank and total internal reflection in the tips. Transmission at the optrode tips with different optical fiber core diameters and light in-coupling interfaces was investigated. At λ = 1.55μm, the highest optrode transmittance of 34.7%, relative to the optical fiber output power, was obtained with a 50-μm multi-mode fiber butt-coupled to the optrode through an intervening medium of index n = 1.66. Maximum power is directed into the optrodes when using fibers with core diameters of 200 μm or less. In addition, the output power varied with the optrode length/taper such that longer and less tapered optrodes exhibited higher light transmission efficiency. Output beam profiles and potential impacts on physiological tests were also examined. Future work is expected to improve USOA efficiency to greater than 64%.
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spelling pubmed-34475622012-09-28 Characterization of a 3D optrode array for infrared neural stimulation Abaya, T.V.F. Diwekar, M. Blair, S. Tathireddy, P. Rieth, L. Clark, G.A. Solzbacher, F. Biomed Opt Express Neuroscience and Brain Imaging This paper characterizes the Utah Slant Optrode Array (USOA) as a means to deliver infrared light deep into tissue. An undoped crystalline silicon (100) substrate was used to fabricate 10 × 10 arrays of optrodes with rows of varying lengths from 0.5 mm to 1.5 mm on a 400-μm pitch. Light delivery from optical fibers and loss mechanisms through these Si optrodes were characterized, with the primary loss mechanisms being Fresnel reflection, coupling, radiation losses from the tapered shank and total internal reflection in the tips. Transmission at the optrode tips with different optical fiber core diameters and light in-coupling interfaces was investigated. At λ = 1.55μm, the highest optrode transmittance of 34.7%, relative to the optical fiber output power, was obtained with a 50-μm multi-mode fiber butt-coupled to the optrode through an intervening medium of index n = 1.66. Maximum power is directed into the optrodes when using fibers with core diameters of 200 μm or less. In addition, the output power varied with the optrode length/taper such that longer and less tapered optrodes exhibited higher light transmission efficiency. Output beam profiles and potential impacts on physiological tests were also examined. Future work is expected to improve USOA efficiency to greater than 64%. Optical Society of America 2012-08-24 /pmc/articles/PMC3447562/ /pubmed/23024914 http://dx.doi.org/10.1364/BOE.3.002200 Text en © 2012 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Neuroscience and Brain Imaging
Abaya, T.V.F.
Diwekar, M.
Blair, S.
Tathireddy, P.
Rieth, L.
Clark, G.A.
Solzbacher, F.
Characterization of a 3D optrode array for infrared neural stimulation
title Characterization of a 3D optrode array for infrared neural stimulation
title_full Characterization of a 3D optrode array for infrared neural stimulation
title_fullStr Characterization of a 3D optrode array for infrared neural stimulation
title_full_unstemmed Characterization of a 3D optrode array for infrared neural stimulation
title_short Characterization of a 3D optrode array for infrared neural stimulation
title_sort characterization of a 3d optrode array for infrared neural stimulation
topic Neuroscience and Brain Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447562/
https://www.ncbi.nlm.nih.gov/pubmed/23024914
http://dx.doi.org/10.1364/BOE.3.002200
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