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Application of non-negative matrix factorization to multispectral FLIM data analysis
Existing methods of interpreting fluorescence lifetime imaging microscopy (FLIM) images are based on comparing the intensity and lifetime values at each pixel with those of known fluorophores. This method becomes unwieldy and subjective in many practical applications where there are several fluoresc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Optical Society of America
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447565/ https://www.ncbi.nlm.nih.gov/pubmed/23024917 http://dx.doi.org/10.1364/BOE.3.002244 |