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Application of non-negative matrix factorization to multispectral FLIM data analysis

Existing methods of interpreting fluorescence lifetime imaging microscopy (FLIM) images are based on comparing the intensity and lifetime values at each pixel with those of known fluorophores. This method becomes unwieldy and subjective in many practical applications where there are several fluoresc...

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Detalles Bibliográficos
Autores principales: Pande, Paritosh, Applegate, Brian E., Jo, Javier A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447565/
https://www.ncbi.nlm.nih.gov/pubmed/23024917
http://dx.doi.org/10.1364/BOE.3.002244

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