Identification and Characterization of Potential Impurities in Raloxifene Hydrochloride

During the synthesis of the bulk drug Raloxifene hydrochloride, eight impurities were observed, four of which were found to be new. All of the impurities were detected using the gradient high performance liquid chromatographic (HPLC) method, whose area percentages ranged from 0.05 to 0.1%. LCMS was...

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Detalles Bibliográficos
Autores principales: Reddy, Reguri Buchi, Goud, Thirumani Venkateshwar, Nagamani, Nagabushanam, Kumar, Nutakki Pavan, Alagudurai, Anandan, Murugan, Raman, Parthasarathy, Kannabiran, Karthikeyan, Vinayagam, Balaji, Perumal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447609/
https://www.ncbi.nlm.nih.gov/pubmed/23008809
http://dx.doi.org/10.3797/scipharm.1204-13

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