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Juxtaglomerular apparatus hyperplasia under dual angiotensin blockade. A footprint of adequate RAS inhibition or a concern for renal fibrosis?

BACKGROUND: Dual renin-angiotensin system blockade with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers has been advocated to minimize proteinuria. However, recent trials have questioned the renal safety of this approach. Our understanding on the molecular effects of dual...

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Detalles Bibliográficos
Autores principales: Fernandez-Fernandez, Beatriz, Ortiz, Alberto, Gomez-Guerrero, Carmen, Barat, Antonio, Martín-Cleary, Catalina, Egido, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447650/
https://www.ncbi.nlm.nih.gov/pubmed/22533828
http://dx.doi.org/10.1186/1471-2369-13-21