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Increased myocardial SERCA expression in early type 2 diabetes mellitus is insulin dependent: In vivo and in vitro data

BACKGROUND: Calcium (Ca2+) handling proteins are known to play a pivotal role in the pathophysiology of cardiomyopathy. However little is known about early changes in the diabetic heart and the impact of insulin treatment (Ins). METHODS: Zucker Diabetic Fatty rats treated with or without insulin (ZD...

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Detalles Bibliográficos
Autores principales:	Fredersdorf, Sabine, Thumann, Christian, Zimmermann, Wolfram H, Vetter, Roland, Graf, Tobias, Luchner, Andreas, Riegger, Günter AJ, Schunkert, Heribert, Eschenhagen, Thomas, Weil, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447673/ https://www.ncbi.nlm.nih.gov/pubmed/22621761 http://dx.doi.org/10.1186/1475-2840-11-57

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