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Time-course microarrays reveal early activation of the immune transcriptome and adipokine dysregulation leads to fibrosis in visceral adipose depots during diet-induced obesity

BACKGROUND: Visceral white adipose tissue (WAT) hypertrophy, adipokine production, inflammation and fibrosis are strongly associated with obesity, but the time-course of these changes in-vivo are not fully understood. Therefore, the aim of this study was to establish the time-course of changes in ad...

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Detalles Bibliográficos
Autores principales: Kwon, Eun-Young, Shin, Su-Kyung, Cho, Yun-Young, Jung, Un Ju, Kim, Eunjung, Park, Taesun, Park, Jung Han Yoon, Yun, Jong Won, McGregor, Robin A, Park, Yong Bok, Choi, Myung-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447724/
https://www.ncbi.nlm.nih.gov/pubmed/22947075
http://dx.doi.org/10.1186/1471-2164-13-450