Centromere Architecture Breakdown Induced by the Viral E3 Ubiquitin Ligase ICP0 Protein of Herpes Simplex Virus Type 1

The viral E3 ubiquitin ligase ICP0 protein has the unique property to temporarily localize at interphase and mitotic centromeres early after infection of cells by the herpes simplex virus type 1 (HSV-1). As a consequence ICP0 induces the proteasomal degradation of several centromeric proteins (CENPs...

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Detalles Bibliográficos
Autores principales: Gross, Sylvain, Catez, Frédéric, Masumoto, Hiroshi, Lomonte, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447814/
https://www.ncbi.nlm.nih.gov/pubmed/23028505
http://dx.doi.org/10.1371/journal.pone.0044227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447814/
https://www.ncbi.nlm.nih.gov/pubmed/23028505
http://dx.doi.org/10.1371/journal.pone.0044227

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