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Centromere Architecture Breakdown Induced by the Viral E3 Ubiquitin Ligase ICP0 Protein of Herpes Simplex Virus Type 1
The viral E3 ubiquitin ligase ICP0 protein has the unique property to temporarily localize at interphase and mitotic centromeres early after infection of cells by the herpes simplex virus type 1 (HSV-1). As a consequence ICP0 induces the proteasomal degradation of several centromeric proteins (CENPs...
Autores principales: | Gross, Sylvain, Catez, Frédéric, Masumoto, Hiroshi, Lomonte, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447814/ https://www.ncbi.nlm.nih.gov/pubmed/23028505 http://dx.doi.org/10.1371/journal.pone.0044227 |
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