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Identification of Genes from the Fungal Pathogen Cryptococcus neoformans Related to Transmigration into the Central Nervous System

BACKGROUND: A mouse brain transmigration assessment (MBTA) was created to investigate the central nervous system (CNS) pathogenesis of cryptococcal meningoencephalitis. METHODOLOGY/PRINCIPAL FINDINGS: Two cryptococcal mutants were identified from a pool of 109 pre-selected mutants that were signatur...

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Detalles Bibliográficos
Autores principales: Tseng, Hsiang-Kuang, Liu, Chang-Pan, Price, Michael S., Jong, Ambrose Y., Chang, Jui-Chih, Toffaletti, Dena L., Betancourt-Quiroz, Marisol, Frazzitta, Aubrey E., Cho, Wen-Long, Perfect, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447876/
https://www.ncbi.nlm.nih.gov/pubmed/23028773
http://dx.doi.org/10.1371/journal.pone.0045083