Connection between Genetic and Clinical Data in Bipolar Disorder

Complex diseases may be associated with combinations of changes in DNA, where the single change has little impact alone. In a previous study of patients with bipolar disorder and controls combinations of SNP genotypes were analyzed, and four large clusters of combinations were found to be significan...

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Detalles Bibliográficos
Autores principales: Mellerup, Erling, Andreassen, Ole, Bennike, Bente, Dam, Henrik, Durovic, Srdjan, Hansen, Thomas, Melle, Ingrid, Møller, Gert Lykke, Mors, Ole, Koefoed, Pernille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447882/
https://www.ncbi.nlm.nih.gov/pubmed/23028568
http://dx.doi.org/10.1371/journal.pone.0044623
Descripción
Sumario:Complex diseases may be associated with combinations of changes in DNA, where the single change has little impact alone. In a previous study of patients with bipolar disorder and controls combinations of SNP genotypes were analyzed, and four large clusters of combinations were found to be significantly associated with bipolar disorder. It has now been found that these clusters may be connected to clinical data.

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