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Heterogeneous Nuclear Ribonucleoprotein F Suppresses Angiotensinogen Gene Expression and Attenuates Hypertension and Kidney Injury in Diabetic Mice
We investigated the impact of heterogeneous nuclear ribonucleoprotein F (hnRNP F) overexpression on angiotensinogen (Agt) gene expression, hypertension, and renal proximal tubular cell (RPTC) injury in high-glucose milieu both in vivo and in vitro. Diabetic Akita transgenic (Tg) mice specifically ov...
Autores principales: | Lo, Chao-Sheng, Chang, Shiao-Ying, Chenier, Isabelle, Filep, Janos G., Ingelfinger, Julie R., Zhang, Shao Ling, Chan, John S.D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447919/ https://www.ncbi.nlm.nih.gov/pubmed/22664958 http://dx.doi.org/10.2337/db11-1349 |
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