Cargando…
High Oxidative Capacity Due to Chronic Exercise Training Attenuates Lipid-Induced Insulin Resistance
Fat accumulation in skeletal muscle combined with low mitochondrial oxidative capacity is associated with insulin resistance (IR). Endurance-trained athletes, characterized by a high oxidative capacity, have elevated intramyocellular lipids, yet are highly insulin sensitive. We tested the hypothesis...
Autores principales: | Phielix, Esther, Meex, Ruth, Ouwens, D. Margriet, Sparks, Lauren, Hoeks, Joris, Schaart, Gert, Moonen-Kornips, Esther, Hesselink, Matthijs K.C., Schrauwen, Patrick |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447923/ https://www.ncbi.nlm.nih.gov/pubmed/22787138 http://dx.doi.org/10.2337/db11-1832 |
Ejemplares similares
-
Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients
por: Phielix, Esther, et al.
Publicado: (2008) -
Relationship of C5L2 Receptor to Skeletal Muscle Substrate Utilization
por: Roy, Christian, et al.
Publicado: (2013) -
Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance
por: Hoeks, Joris, et al.
Publicado: (2010) -
ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity
por: Sparks, Lauren M., et al.
Publicado: (2016) -
Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity
por: Meex, Ruth C.R., et al.
Publicado: (2010)