Tetraspanin Is Required for Generation of Reactive Oxygen Species by the Dual Oxidase System in Caenorhabditis elegans

Reactive oxygen species (ROS) are toxic but essential molecules responsible for host defense and cellular signaling. Conserved NADPH oxidase (NOX) family enzymes direct the regulated production of ROS. Hydrogen peroxide (H(2)O(2)) generated by dual oxidases (DUOXs), a member of the NOX family, is cr...

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Detalles Bibliográficos
Autores principales: Moribe, Hiroki, Konakawa, Ryouji, Koga, Daisuke, Ushiki, Tatsuo, Nakamura, Kuniaki, Mekada, Eisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447965/
https://www.ncbi.nlm.nih.gov/pubmed/23028364
http://dx.doi.org/10.1371/journal.pgen.1002957

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