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What Evidence Is There for the Homology of Protein-Protein Interactions?
The notion that sequence homology implies functional similarity underlies much of computational biology. In the case of protein-protein interactions, an interaction can be inferred between two proteins on the basis that sequence-similar proteins have been observed to interact. The use of transferred...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447968/ https://www.ncbi.nlm.nih.gov/pubmed/23028270 http://dx.doi.org/10.1371/journal.pcbi.1002645 |