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Structural Investigation of MscL Gating Using Experimental Data and Coarse Grained MD Simulations
The mechanosensitive channel of large conductance (MscL) has become a model system in which to understand mechanosensation, a process involved in osmoregulation and many other physiological functions. While a high resolution closed state structure is available, details of the open structure and the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447979/ https://www.ncbi.nlm.nih.gov/pubmed/23028281 http://dx.doi.org/10.1371/journal.pcbi.1002683 |