Thyroid hormone induces sprouting angiogenesis in adult heart of hypothyroid mice through the PDGF-Akt pathway

Study of physiological angiogenesis and associated signalling mechanisms in adult heart has been limited by the lack of a robust animal model. We investigated thyroid hormone-induced sprouting angiogenesis and the underlying mechanism. Hypothyroidism was induced in C57BL/6J mice by feeding with prop...

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Detalles Bibliográficos
Autores principales: Chen, Jinghai, Ortmeier, Steven B, Savinova, Olga V, Nareddy, Vijaya B, Beyer, April J, Wang, Dajun, Gerdes, A Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448001/
https://www.ncbi.nlm.nih.gov/pubmed/22681587
http://dx.doi.org/10.1111/j.1582-4934.2012.01593.x

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