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Activated Ribonucleotides Undergo a Sugar Pucker Switch upon Binding to a Single-Stranded RNA Template
[Image: see text] Template-directed polymerization of chemically activated ribonucleotide monomers, such as nucleotide 5′-phosphorimidazolides, has been studied as a model for nonenzymatic RNA replication during the origin of life. Kinetic studies of the polymerization of various nucleotide monomers...
Autores principales: | Zhang, Na, Zhang, Shenglong, Szostak, Jack W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448298/ https://www.ncbi.nlm.nih.gov/pubmed/22296305 http://dx.doi.org/10.1021/ja212027q |
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