Cargando…

PEG-Labeled Nucleotides and Nanopore Detection for Single Molecule DNA Sequencing by Synthesis

We describe a novel single molecule nanopore-based sequencing by synthesis (Nano-SBS) strategy that can accurately distinguish four bases by detecting 4 different sized tags released from 5′-phosphate-modified nucleotides. The basic principle is as follows. As each nucleotide is incorporated into th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumar, Shiv, Tao, Chuanjuan, Chien, Minchen, Hellner, Brittney, Balijepalli, Arvind, Robertson, Joseph W. F., Li, Zengmin, Russo, James J., Reiner, Joseph E., Kasianowicz, John J., Ju, Jingyue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448304/ https://www.ncbi.nlm.nih.gov/pubmed/23002425 http://dx.doi.org/10.1038/srep00684

Ejemplares similares

Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase
por: Chien, Minchen, et al.
Publicado: (2020)

Nucleotide analogues as inhibitors of SARS‐CoV Polymerase
por: Ju, Jingyue, et al.
Publicado: (2020)

A library of nucleotide analogues terminate RNA synthesis catalyzed by polymerases of coronaviruses that cause SARS and COVID-19
por: Jockusch, Steffen, et al.
Publicado: (2020)

Sofosbuvir terminated RNA is more resistant to SARS-CoV-2 proofreader than RNA terminated by Remdesivir
por: Jockusch, Steffen, et al.
Publicado: (2020)

Identifying Structural Features of Nucleotide Analogues to Overcome SARS-CoV-2 Exonuclease Activity
por: Wang, Xuanting, et al.
Publicado: (2022)

Quantifying Short-Lived Events in Multistate Ionic Current Measurements
por: Balijepalli, Arvind, et al.
Publicado: (2014)

Correction to Quantifying Short-Lived Events in Multistate Ionic Channel Measurements
por: Balijepalli, Arvind, et al.
Publicado: (2015)

Molecular beacons with intrinsically fluorescent nucleotides
por: Martí, Angel A., et al.
Publicado: (2006)

PLLA-PEG-TCH-labeled bioactive molecule nanofibers for tissue engineering
por: Chen, Jun, et al.
Publicado: (2011)

Laser-based temperature control to study the roles of entropy and enthalpy in polymer-nanopore interactions
por: Angevine, Christopher E., et al.
Publicado: (2021)

Combination of Antiviral Drugs to Inhibit SARS-CoV-2 Polymerase and Exonuclease as Potential COVID-19 Therapeutics
por: Wang, Xuanting, et al.
Publicado: (2021)

Combination of antiviral drugs inhibits SARS-CoV-2 polymerase and exonuclease and demonstrates COVID-19 therapeutic potential in viral cell culture
por: Wang, Xuanting, et al.
Publicado: (2022)

Prognostic Values of microRNAs in Colorectal Cancer
por: Xi, Yaguang, et al.
Publicado: (2007)

Active Delivery of Single DNA Molecules into a Plasmonic Nanopore for Label-Free Optical Sensing
por: Shi, Xin, et al.
Publicado: (2018)

Label-Free Optical Detection of Biomolecular Translocation through Nanopore Arrays
por: Ivankin, Andrey, et al.
Publicado: (2014)

Nucleotide Discrimination with DNA Immobilized in the MspA Nanopore
por: Manrao, Elizabeth A., et al.
Publicado: (2011)

Methplotlib: analysis of modified nucleotides from nanopore sequencing
por: De Coster, Wouter, et al.
Publicado: (2020)

A solid-state nanopore-based single-molecule approach for label-free characterization of plant polysaccharides
por: Cai, Yao, et al.
Publicado: (2020)

Label-free single-molecule identification of telomere G-quadruplexes with a solid-state nanopore sensor
por: Wang, Sen, et al.
Publicado: (2020)

Label-Free Optical Analysis of Biomolecules in Solid-State Nanopores: Toward Single-Molecule Protein Sequencing
por: Zhao, Yingqi, et al.
Publicado: (2022)

Nucleotide and structural label identification in single RNA molecules with quantum tunneling spectroscopy
por: Abel, Gary R., et al.
Publicado: (2018)

Biological nanopores for single-molecule sensing
por: Mayer, Simon Finn, et al.
Publicado: (2022)

Correcting modification-mediated errors in nanopore sequencing by nucleotide demodification and reference-based correction
por: Chiou, Chien-Shun, et al.
Publicado: (2023)

Immune drivers of HBsAg loss in HBeAg-negative CHB patients after stopping nucleotide analog and administration of Peg-IFN
por: Islam, Mojahidul, et al.
Publicado: (2023)

Using Amino-Labeled Nucleotide Probes for Simultaneous Single Molecule RNA-DNA FISH
por: Basu, Reelina, et al.
Publicado: (2014)

Systematic and stochastic influences on the performance of the MinION nanopore sequencer across a range of nucleotide bias
por: Krishnakumar, Raga, et al.
Publicado: (2018)

Labeling Sepsis: Many Square Pegs into Countless Round Roles
por: Weiss, Scott L., et al.
Publicado: (2021)

Synthesis and comparative evaluation of (177)Lu-labeled PEG and non-PEG variant peptides as HER2-targeting probes
por: Sharma, Amit Kumar, et al.
Publicado: (2022)

Herding cats: Label-based approaches in protein translocation through nanopore sensors for single-molecule protein sequence analysis
por: Motone, Keisuke, et al.
Publicado: (2021)

Replication of Individual DNA Molecules under Electronic Control Using a Protein Nanopore
por: Olasagasti, Felix, et al.
Publicado: (2010)

Biochip for the Detection of Bacillus anthracis Lethal Factor and Therapeutic Agents against Anthrax Toxins
por: Silin, Vitalii, et al.
Publicado: (2016)

Nanometer-Scale Pores: Potential Applications for Analyte Detection and DNA Characterization
por: Kasianowicz, John J.
Publicado: (2002)

Single-molecule sensing electrode embedded in-plane nanopore
por: Tsutsui, Makusu, et al.
Publicado: (2011)

Nanopore detection of DNA molecules in magnesium chloride solutions
por: Zhang, Yin, et al.
Publicado: (2013)

Single-Molecule Study of Proteins by Biological Nanopore Sensors
por: Wu, Dongmei, et al.
Publicado: (2014)

Gated Single-Molecule Transport in Double-Barreled Nanopores
por: Xue, Liang, et al.
Publicado: (2018)

Single-molecule protein identification by sub-nanopore sensors
por: Kolmogorov, Mikhail, et al.
Publicado: (2017)

Detection of Biological Molecules Using Nanopore Sensing Techniques
por: Șoldănescu, Iuliana, et al.
Publicado: (2023)

Towards inferring nanopore sequencing ionic currents from nucleotide chemical structures
por: Ding, Hongxu, et al.
Publicado: (2021)

Single nucleotide detection using bilayer MoS(2) nanopores with high efficiency
por: Sen, Payel, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8sqpffnisfjskqu6a96eiu7i0o