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Evaluation of the anaesthetic properties and tolerance of 1:100,000 articaine versus 1:100,000 lidocaine. A comparative study in surgery of the lower third molar
Objectives: To evaluate the anaesthetic properties and tolerance of articaine versus lidocaine at equal vasoconstrictor concentration. Study Design: A total of 96 male and female patients who underwent surgical treatment of the lower third molar participated. Patients were randomly assigned to artic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448332/ https://www.ncbi.nlm.nih.gov/pubmed/22143691 http://dx.doi.org/10.4317/medoral.17414 |
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author | Martínez-Rodríguez, Natalia Barona-Dorado, Cristina Martín-Arés, María Cortés-Bretón-Brinkman, Jorge Martínez-González, José M. |
author_facet | Martínez-Rodríguez, Natalia Barona-Dorado, Cristina Martín-Arés, María Cortés-Bretón-Brinkman, Jorge Martínez-González, José M. |
author_sort | Martínez-Rodríguez, Natalia |
collection | PubMed |
description | Objectives: To evaluate the anaesthetic properties and tolerance of articaine versus lidocaine at equal vasoconstrictor concentration. Study Design: A total of 96 male and female patients who underwent surgical treatment of the lower third molar participated. Patients were randomly assigned to articaine hydrochloride with epinephrine 1:100,000 and lidocaine hydrochloride with epinephrine 1:100,000. The variables analysed were latency period, duration of anaesthetic effect, tolerance and adverse reactions. Results: Both the latency period and the duration of anaesthetic effect were greater for articaine, although the differences were not statistically significant. Latency: mean difference of 2.70 ± 2.12 minutes (95%CI of -1.51 minutes - 6.92 minutes). Duration: mean difference of -33 minutes 5 seconds ± 31 minutes (95% CI -1 hour 35 minutes - 29 minutes). There were 4 adverse events that did not require the patients to be withdrawn from the study. Conclusions: The anaesthetics in this study have very similar properties for use in surgery and have demonstrated a good safety and tolerability profile Key words: Articaine, lidocaine, vasoconstrictor, adverse reactions. |
format | Online Article Text |
id | pubmed-3448332 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-34483322012-10-11 Evaluation of the anaesthetic properties and tolerance of 1:100,000 articaine versus 1:100,000 lidocaine. A comparative study in surgery of the lower third molar Martínez-Rodríguez, Natalia Barona-Dorado, Cristina Martín-Arés, María Cortés-Bretón-Brinkman, Jorge Martínez-González, José M. Med Oral Patol Oral Cir Bucal Research-Article Objectives: To evaluate the anaesthetic properties and tolerance of articaine versus lidocaine at equal vasoconstrictor concentration. Study Design: A total of 96 male and female patients who underwent surgical treatment of the lower third molar participated. Patients were randomly assigned to articaine hydrochloride with epinephrine 1:100,000 and lidocaine hydrochloride with epinephrine 1:100,000. The variables analysed were latency period, duration of anaesthetic effect, tolerance and adverse reactions. Results: Both the latency period and the duration of anaesthetic effect were greater for articaine, although the differences were not statistically significant. Latency: mean difference of 2.70 ± 2.12 minutes (95%CI of -1.51 minutes - 6.92 minutes). Duration: mean difference of -33 minutes 5 seconds ± 31 minutes (95% CI -1 hour 35 minutes - 29 minutes). There were 4 adverse events that did not require the patients to be withdrawn from the study. Conclusions: The anaesthetics in this study have very similar properties for use in surgery and have demonstrated a good safety and tolerability profile Key words: Articaine, lidocaine, vasoconstrictor, adverse reactions. Medicina Oral S.L. 2012-03 2011-12-06 /pmc/articles/PMC3448332/ /pubmed/22143691 http://dx.doi.org/10.4317/medoral.17414 Text en Copyright: © 2012 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research-Article Martínez-Rodríguez, Natalia Barona-Dorado, Cristina Martín-Arés, María Cortés-Bretón-Brinkman, Jorge Martínez-González, José M. Evaluation of the anaesthetic properties and tolerance of 1:100,000 articaine versus 1:100,000 lidocaine. A comparative study in surgery of the lower third molar |
title | Evaluation of the anaesthetic properties and tolerance of 1:100,000
articaine versus 1:100,000 lidocaine. A comparative
study in surgery of the lower third molar |
title_full | Evaluation of the anaesthetic properties and tolerance of 1:100,000
articaine versus 1:100,000 lidocaine. A comparative
study in surgery of the lower third molar |
title_fullStr | Evaluation of the anaesthetic properties and tolerance of 1:100,000
articaine versus 1:100,000 lidocaine. A comparative
study in surgery of the lower third molar |
title_full_unstemmed | Evaluation of the anaesthetic properties and tolerance of 1:100,000
articaine versus 1:100,000 lidocaine. A comparative
study in surgery of the lower third molar |
title_short | Evaluation of the anaesthetic properties and tolerance of 1:100,000
articaine versus 1:100,000 lidocaine. A comparative
study in surgery of the lower third molar |
title_sort | evaluation of the anaesthetic properties and tolerance of 1:100,000
articaine versus 1:100,000 lidocaine. a comparative
study in surgery of the lower third molar |
topic | Research-Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448332/ https://www.ncbi.nlm.nih.gov/pubmed/22143691 http://dx.doi.org/10.4317/medoral.17414 |
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