Cargando…

Computed tomography and pathological findings of five nasal neurilemmomas

OBJECTIVES: Neurilemmomas are benign tumors deriving from Schwann cells of the nerve sheath. They occur in all parts of the body. The highest incidence of neurilemmoma is in the head and neck region (38–45%), but involvement of the nose and paranasal sinus is quite rare, with only sporadic cases hav...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Jing, Bao, Yang-Yang, Cheng, Ke-Jia, Zhou, Shui-Hong, Ruan, Ling-Xiang, Zheng, Zhou-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448516/
https://www.ncbi.nlm.nih.gov/pubmed/22621416
http://dx.doi.org/10.1186/1758-3284-4-26
_version_ 1782244262490931200
author Hu, Jing
Bao, Yang-Yang
Cheng, Ke-Jia
Zhou, Shui-Hong
Ruan, Ling-Xiang
Zheng, Zhou-Jun
author_facet Hu, Jing
Bao, Yang-Yang
Cheng, Ke-Jia
Zhou, Shui-Hong
Ruan, Ling-Xiang
Zheng, Zhou-Jun
author_sort Hu, Jing
collection PubMed
description OBJECTIVES: Neurilemmomas are benign tumors deriving from Schwann cells of the nerve sheath. They occur in all parts of the body. The highest incidence of neurilemmoma is in the head and neck region (38–45%), but involvement of the nose and paranasal sinus is quite rare, with only sporadic cases having been reported in the world literature. Fewer than 4% of these tumors involve the nasal cavity and paranasal sinuses. We describe the clinical, pathologic, and computed tomography (CT) features of five nasal neurilemmomas. METHODOLOGY: CT features of five patients with nasal schwannoma proved by operation and pathology were investigated. RESULTS: Schwannomas tend to be solitary and are usually well-circumscribed tumors with an oval, round or fusiform shape in the unilateral nasal cavity. The lesions usually have a mottled central lucency with peripheral intensification on contrast-enhanced CT scans. The heterogeneous appearance is related to areas of increased vascularity with adjacent non-enhancing cystic or necrotic regions. CONCLUSIONS: Schwannoma should be considered in the differential of unusual nasal masses. Certain clinical and CT patterns may be of use in the differential diagnosis.
format Online
Article
Text
id pubmed-3448516
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-34485162012-09-22 Computed tomography and pathological findings of five nasal neurilemmomas Hu, Jing Bao, Yang-Yang Cheng, Ke-Jia Zhou, Shui-Hong Ruan, Ling-Xiang Zheng, Zhou-Jun Head Neck Oncol Research OBJECTIVES: Neurilemmomas are benign tumors deriving from Schwann cells of the nerve sheath. They occur in all parts of the body. The highest incidence of neurilemmoma is in the head and neck region (38–45%), but involvement of the nose and paranasal sinus is quite rare, with only sporadic cases having been reported in the world literature. Fewer than 4% of these tumors involve the nasal cavity and paranasal sinuses. We describe the clinical, pathologic, and computed tomography (CT) features of five nasal neurilemmomas. METHODOLOGY: CT features of five patients with nasal schwannoma proved by operation and pathology were investigated. RESULTS: Schwannomas tend to be solitary and are usually well-circumscribed tumors with an oval, round or fusiform shape in the unilateral nasal cavity. The lesions usually have a mottled central lucency with peripheral intensification on contrast-enhanced CT scans. The heterogeneous appearance is related to areas of increased vascularity with adjacent non-enhancing cystic or necrotic regions. CONCLUSIONS: Schwannoma should be considered in the differential of unusual nasal masses. Certain clinical and CT patterns may be of use in the differential diagnosis. BioMed Central 2012-05-23 /pmc/articles/PMC3448516/ /pubmed/22621416 http://dx.doi.org/10.1186/1758-3284-4-26 Text en Copyright © 2012 Hu et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Hu, Jing
Bao, Yang-Yang
Cheng, Ke-Jia
Zhou, Shui-Hong
Ruan, Ling-Xiang
Zheng, Zhou-Jun
Computed tomography and pathological findings of five nasal neurilemmomas
title Computed tomography and pathological findings of five nasal neurilemmomas
title_full Computed tomography and pathological findings of five nasal neurilemmomas
title_fullStr Computed tomography and pathological findings of five nasal neurilemmomas
title_full_unstemmed Computed tomography and pathological findings of five nasal neurilemmomas
title_short Computed tomography and pathological findings of five nasal neurilemmomas
title_sort computed tomography and pathological findings of five nasal neurilemmomas
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448516/
https://www.ncbi.nlm.nih.gov/pubmed/22621416
http://dx.doi.org/10.1186/1758-3284-4-26
work_keys_str_mv AT hujing computedtomographyandpathologicalfindingsoffivenasalneurilemmomas
AT baoyangyang computedtomographyandpathologicalfindingsoffivenasalneurilemmomas
AT chengkejia computedtomographyandpathologicalfindingsoffivenasalneurilemmomas
AT zhoushuihong computedtomographyandpathologicalfindingsoffivenasalneurilemmomas
AT ruanlingxiang computedtomographyandpathologicalfindingsoffivenasalneurilemmomas
AT zhengzhoujun computedtomographyandpathologicalfindingsoffivenasalneurilemmomas