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Computed tomography and pathological findings of five nasal neurilemmomas
OBJECTIVES: Neurilemmomas are benign tumors deriving from Schwann cells of the nerve sheath. They occur in all parts of the body. The highest incidence of neurilemmoma is in the head and neck region (38–45%), but involvement of the nose and paranasal sinus is quite rare, with only sporadic cases hav...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448516/ https://www.ncbi.nlm.nih.gov/pubmed/22621416 http://dx.doi.org/10.1186/1758-3284-4-26 |
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author | Hu, Jing Bao, Yang-Yang Cheng, Ke-Jia Zhou, Shui-Hong Ruan, Ling-Xiang Zheng, Zhou-Jun |
author_facet | Hu, Jing Bao, Yang-Yang Cheng, Ke-Jia Zhou, Shui-Hong Ruan, Ling-Xiang Zheng, Zhou-Jun |
author_sort | Hu, Jing |
collection | PubMed |
description | OBJECTIVES: Neurilemmomas are benign tumors deriving from Schwann cells of the nerve sheath. They occur in all parts of the body. The highest incidence of neurilemmoma is in the head and neck region (38–45%), but involvement of the nose and paranasal sinus is quite rare, with only sporadic cases having been reported in the world literature. Fewer than 4% of these tumors involve the nasal cavity and paranasal sinuses. We describe the clinical, pathologic, and computed tomography (CT) features of five nasal neurilemmomas. METHODOLOGY: CT features of five patients with nasal schwannoma proved by operation and pathology were investigated. RESULTS: Schwannomas tend to be solitary and are usually well-circumscribed tumors with an oval, round or fusiform shape in the unilateral nasal cavity. The lesions usually have a mottled central lucency with peripheral intensification on contrast-enhanced CT scans. The heterogeneous appearance is related to areas of increased vascularity with adjacent non-enhancing cystic or necrotic regions. CONCLUSIONS: Schwannoma should be considered in the differential of unusual nasal masses. Certain clinical and CT patterns may be of use in the differential diagnosis. |
format | Online Article Text |
id | pubmed-3448516 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-34485162012-09-22 Computed tomography and pathological findings of five nasal neurilemmomas Hu, Jing Bao, Yang-Yang Cheng, Ke-Jia Zhou, Shui-Hong Ruan, Ling-Xiang Zheng, Zhou-Jun Head Neck Oncol Research OBJECTIVES: Neurilemmomas are benign tumors deriving from Schwann cells of the nerve sheath. They occur in all parts of the body. The highest incidence of neurilemmoma is in the head and neck region (38–45%), but involvement of the nose and paranasal sinus is quite rare, with only sporadic cases having been reported in the world literature. Fewer than 4% of these tumors involve the nasal cavity and paranasal sinuses. We describe the clinical, pathologic, and computed tomography (CT) features of five nasal neurilemmomas. METHODOLOGY: CT features of five patients with nasal schwannoma proved by operation and pathology were investigated. RESULTS: Schwannomas tend to be solitary and are usually well-circumscribed tumors with an oval, round or fusiform shape in the unilateral nasal cavity. The lesions usually have a mottled central lucency with peripheral intensification on contrast-enhanced CT scans. The heterogeneous appearance is related to areas of increased vascularity with adjacent non-enhancing cystic or necrotic regions. CONCLUSIONS: Schwannoma should be considered in the differential of unusual nasal masses. Certain clinical and CT patterns may be of use in the differential diagnosis. BioMed Central 2012-05-23 /pmc/articles/PMC3448516/ /pubmed/22621416 http://dx.doi.org/10.1186/1758-3284-4-26 Text en Copyright © 2012 Hu et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Hu, Jing Bao, Yang-Yang Cheng, Ke-Jia Zhou, Shui-Hong Ruan, Ling-Xiang Zheng, Zhou-Jun Computed tomography and pathological findings of five nasal neurilemmomas |
title | Computed tomography and pathological findings of five nasal neurilemmomas |
title_full | Computed tomography and pathological findings of five nasal neurilemmomas |
title_fullStr | Computed tomography and pathological findings of five nasal neurilemmomas |
title_full_unstemmed | Computed tomography and pathological findings of five nasal neurilemmomas |
title_short | Computed tomography and pathological findings of five nasal neurilemmomas |
title_sort | computed tomography and pathological findings of five nasal neurilemmomas |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448516/ https://www.ncbi.nlm.nih.gov/pubmed/22621416 http://dx.doi.org/10.1186/1758-3284-4-26 |
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