Increased ratio of anti-apoptotic to pro-apoptotic Bcl2 gene-family members in lithium-responders one month after treatment initiation

BACKGROUND: Lithium is considered by many as the gold standard medication in the management of bipolar disorder (BD). However, the clinical response to lithium is heterogeneous, and the molecular basis for this difference in response is unknown. In the present study, we sought to determine how the p...

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Detalles Bibliográficos
Autores principales: Lowthert, Lori, Leffert, Janine, Lin, Aiping, Umlauf, Sheila, Maloney, Kathleen, Muralidharan, Anjana, Lorberg, Boris, Mane, Shrikant, Zhao, Hongyu, Sinha, Rajita, Bhagwagar, Zubin, Beech, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448519/
https://www.ncbi.nlm.nih.gov/pubmed/22967286
http://dx.doi.org/10.1186/2045-5380-2-15

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