Characterization of Molecular Determinants of the Conformational Stability of Macrophage Migration Inhibitory Factor: Leucine 46 Hydrophobic Pocket

Macrophage Migration Inhibitory Factor (MIF) is a key mediator of inflammatory responses and innate immunity and has been implicated in the pathogenesis of several inflammatory and autoimmune diseases. The oligomerization of MIF, more specifically trimer formation, is essential for its keto-enol tau...

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Detalles Bibliográficos
Autores principales: El-Turk, Farah, Fauvet, Bruno, Ashrafi, Amer, Ouertatani-Sakouhi, Hajer, Cho, Min-Kyu, Neri, Marilisa, Cascella, Michele, Rothlisberger, Ursula, Pojer, Florence, Zweckstetter, Markus, Lashuel, Hilal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448610/
https://www.ncbi.nlm.nih.gov/pubmed/23028743
http://dx.doi.org/10.1371/journal.pone.0045024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448610/
https://www.ncbi.nlm.nih.gov/pubmed/23028743
http://dx.doi.org/10.1371/journal.pone.0045024

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