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Development of a Fetal Weight Chart Using Serial Trans-Abdominal Ultrasound in an East African Population: A Longitudinal Observational Study

OBJECTIVE: To produce a fetal weight chart representative of a Tanzanian population, and compare it to weight charts from Sub-Saharan Africa and the developed world. METHODS: A longitudinal observational study in Northeastern Tanzania. Pregnant women were followed throughout pregnancy with serial tr...

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Autores principales: Schmiegelow, Christentze, Scheike, Thomas, Oesterholt, Mayke, Minja, Daniel, Pehrson, Caroline, Magistrado, Pamela, Lemnge, Martha, Rasch, Vibeke, Lusingu, John, Theander, Thor G., Nielsen, Birgitte Bruun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448622/
https://www.ncbi.nlm.nih.gov/pubmed/23028617
http://dx.doi.org/10.1371/journal.pone.0044773
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author Schmiegelow, Christentze
Scheike, Thomas
Oesterholt, Mayke
Minja, Daniel
Pehrson, Caroline
Magistrado, Pamela
Lemnge, Martha
Rasch, Vibeke
Lusingu, John
Theander, Thor G.
Nielsen, Birgitte Bruun
author_facet Schmiegelow, Christentze
Scheike, Thomas
Oesterholt, Mayke
Minja, Daniel
Pehrson, Caroline
Magistrado, Pamela
Lemnge, Martha
Rasch, Vibeke
Lusingu, John
Theander, Thor G.
Nielsen, Birgitte Bruun
author_sort Schmiegelow, Christentze
collection PubMed
description OBJECTIVE: To produce a fetal weight chart representative of a Tanzanian population, and compare it to weight charts from Sub-Saharan Africa and the developed world. METHODS: A longitudinal observational study in Northeastern Tanzania. Pregnant women were followed throughout pregnancy with serial trans-abdominal ultrasound. All pregnancies with pathology were excluded and a chart representing the optimal growth potential was developed using fetal weights and birth weights. The weight chart was compared to a chart from Congo, a chart representing a white population, and a chart representing a white population but adapted to the study population. The prevalence of SGA was assessed using all four charts. RESULTS: A total of 2193 weight measurements from 583 fetuses/newborns were included in the fetal weight chart. Our chart had lower percentiles than all the other charts. Most importantly, in the end of pregnancy, the 10(th) percentiles deviated substantially causing an overestimation of the true prevalence of SGA newborns if our chart had not been used. CONCLUSIONS: We developed a weight chart representative for a Tanzanian population and provide evidence for the necessity of developing regional specific weight charts for correct identification of SGA. Our weight chart is an important tool that can be used for clinical risk assessments of newborns and for evaluating the effect of intrauterine exposures on fetal and newborn weight.
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spelling pubmed-34486222012-10-01 Development of a Fetal Weight Chart Using Serial Trans-Abdominal Ultrasound in an East African Population: A Longitudinal Observational Study Schmiegelow, Christentze Scheike, Thomas Oesterholt, Mayke Minja, Daniel Pehrson, Caroline Magistrado, Pamela Lemnge, Martha Rasch, Vibeke Lusingu, John Theander, Thor G. Nielsen, Birgitte Bruun PLoS One Research Article OBJECTIVE: To produce a fetal weight chart representative of a Tanzanian population, and compare it to weight charts from Sub-Saharan Africa and the developed world. METHODS: A longitudinal observational study in Northeastern Tanzania. Pregnant women were followed throughout pregnancy with serial trans-abdominal ultrasound. All pregnancies with pathology were excluded and a chart representing the optimal growth potential was developed using fetal weights and birth weights. The weight chart was compared to a chart from Congo, a chart representing a white population, and a chart representing a white population but adapted to the study population. The prevalence of SGA was assessed using all four charts. RESULTS: A total of 2193 weight measurements from 583 fetuses/newborns were included in the fetal weight chart. Our chart had lower percentiles than all the other charts. Most importantly, in the end of pregnancy, the 10(th) percentiles deviated substantially causing an overestimation of the true prevalence of SGA newborns if our chart had not been used. CONCLUSIONS: We developed a weight chart representative for a Tanzanian population and provide evidence for the necessity of developing regional specific weight charts for correct identification of SGA. Our weight chart is an important tool that can be used for clinical risk assessments of newborns and for evaluating the effect of intrauterine exposures on fetal and newborn weight. Public Library of Science 2012-09-21 /pmc/articles/PMC3448622/ /pubmed/23028617 http://dx.doi.org/10.1371/journal.pone.0044773 Text en © 2012 Schmiegelow et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Schmiegelow, Christentze
Scheike, Thomas
Oesterholt, Mayke
Minja, Daniel
Pehrson, Caroline
Magistrado, Pamela
Lemnge, Martha
Rasch, Vibeke
Lusingu, John
Theander, Thor G.
Nielsen, Birgitte Bruun
Development of a Fetal Weight Chart Using Serial Trans-Abdominal Ultrasound in an East African Population: A Longitudinal Observational Study
title Development of a Fetal Weight Chart Using Serial Trans-Abdominal Ultrasound in an East African Population: A Longitudinal Observational Study
title_full Development of a Fetal Weight Chart Using Serial Trans-Abdominal Ultrasound in an East African Population: A Longitudinal Observational Study
title_fullStr Development of a Fetal Weight Chart Using Serial Trans-Abdominal Ultrasound in an East African Population: A Longitudinal Observational Study
title_full_unstemmed Development of a Fetal Weight Chart Using Serial Trans-Abdominal Ultrasound in an East African Population: A Longitudinal Observational Study
title_short Development of a Fetal Weight Chart Using Serial Trans-Abdominal Ultrasound in an East African Population: A Longitudinal Observational Study
title_sort development of a fetal weight chart using serial trans-abdominal ultrasound in an east african population: a longitudinal observational study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448622/
https://www.ncbi.nlm.nih.gov/pubmed/23028617
http://dx.doi.org/10.1371/journal.pone.0044773
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