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Focal Adhesion Kinase Plays a Role in Osteoblast Mechanotransduction In Vitro but Does Not Affect Load-Induced Bone Formation In Vivo
A healthy skeleton relies on bone's ability to respond to external mechanical forces. The molecular mechanisms by which bone cells sense and convert mechanical stimuli into biochemical signals, a process known as mechanotransduction, are unclear. Focal adhesions play a critical role in cell sur...
Autores principales: | Castillo, Alesha B., Blundo, Jennifer T., Chen, Julia C., Lee, Kristen L., Yereddi, Nikitha Reddy, Jang, Eugene, Kumar, Shefali, Tang, W. Joyce, Zarrin, Sarah, Kim, Jae-Beom, Jacobs, Christopher R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448625/ https://www.ncbi.nlm.nih.gov/pubmed/23028449 http://dx.doi.org/10.1371/journal.pone.0043291 |
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