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Melanoma-Associated Cancer-Testis Antigen 16 (CT16) Regulates the Expression of Apoptotic and Antiapoptotic Genes and Promotes Cell Survival

Cancer-testis (CT) antigens are predominantly expressed in testis or placenta, but absent in most adult tissues. During malignant transformation CT genes are often activated. CT antigen 16 (CT16, PAGE5) is frequently expressed in advanced melanoma but its biological function has been unknown. To exa...

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Detalles Bibliográficos
Autores principales: Nylund, Camilla, Rappu, Pekka, Pakula, Eveliina, Heino, Aleksi, Laato, Laura, Elo, Laura L., Vihinen, Pia, Pyrhönen, Seppo, Owen, Gethin R., Larjava, Hannu, Kallajoki, Markku, Heino, Jyrki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448647/
https://www.ncbi.nlm.nih.gov/pubmed/23028975
http://dx.doi.org/10.1371/journal.pone.0045382