4-1BB Signaling Breaks the Tolerance of Maternal CD8(+) T Cells That Are Reactive with Alloantigens

4-1BB (CD137, TNFRSF9), a member of the activation-induced tumor necrosis factor receptor family, is a powerful T-cell costimulatory molecule. It generally enhances CD8(+) T responses and even breaks the tolerance of CD8(+) T cells in an antigen-specific manner. In the present study we found that it...

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Detalles Bibliográficos
Autores principales: Kim, Kwang H., Choi, Beom K., Kim, Jung D., Kim, Young H., Lee, Sun K., Suh, Jae H., Lee, Sang C., Kang, Sang W., Kwon, Byoung S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448654/
https://www.ncbi.nlm.nih.gov/pubmed/23029041
http://dx.doi.org/10.1371/journal.pone.0045481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448654/
https://www.ncbi.nlm.nih.gov/pubmed/23029041
http://dx.doi.org/10.1371/journal.pone.0045481

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