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Insulin-Like Growth Factor-I E-Peptide Activity Is Dependent on the IGF-I Receptor
Insulin-like growth factor-I (IGF-I) is an essential growth factor that regulates the processes necessary for cell proliferation, differentiation, and survival. The Igf1 gene encodes mature IGF-I and a carboxy-terminal extension called the E-peptide. In rodents, alternative splicing and post-transla...
Autores principales: | Brisson, Becky K., Barton, Elisabeth R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448668/ https://www.ncbi.nlm.nih.gov/pubmed/23029120 http://dx.doi.org/10.1371/journal.pone.0045588 |
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